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Two types of projection neurons in human striatum: Peculiarities of their somatodendritic structure in ventral and dorsal striatum

“…The mesencephalic projections of the nucleus accumbens terminate on spiny neurons and originate predominantly from the ventral mesencephalic tegmentum, while projections of the dorsal striatum originate predominantly from the substantia nigra [12]. Thalamic afferents of the nucleus accumbens originate from neurons of the midline nuclei, which are considered as the integral elements of the limbic system, while thalamic projections of the dorsal striatum originate from the nuclei connected to the cortex and subcortical structures involved (among other functions) into the work of the motor system [3]. The amygdala afferents of the nucleus accumbens and dorsal striatum originate from common sources: mostly, from the nuclei of the basolateral complex [2].…”