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doi:10.13040/ijpsr.0975-8232.8(5).1953-58

Cited by 2 publications

(3 citation statements)

References 14 publications

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“…The major constituents detected in the essential oils extracted from three Scrophularia species growing wild in Iran, including S. amplexicaulis , S. frigida , and S. subaphylla , were eugenol and linalool [ 37 , 38 , 39 ]. The essential oil extracted from the aerial parts of Scrophularia deserti from Vietnam and Iran contained mainly α-pinene [ 40 ]. The main constituents of S. oxysepala were phytol, methyl benzyl alcohol, dehydrodieugenol, methyl benzaldehyde, and eugenol [ 35 ].…”

Section: Resultsmentioning

confidence: 99%

Scrophularia peyronii Post. from Jordan: Chemical Composition of Essential Oil and Phytochemical Profiling of Crude Extracts and Their In Vitro Antioxidant Activity

Al-Dalahmeh,

Almahmoud,

Al-Bataineh

et al. 2023

Life

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The genus Scrophularia is one of the largest genera belonging to the Scrophulariaceae family. Different members of the genus exhibit an interesting, wide spectrum of bioactivities. Accordingly, the current study aimed to investigate, for the first time, the chemical composition of the essential oil of Scrophularia peyronii Post. from Jordan. Additionally, extracts obtained from the aerial parts with solvents of different polarities were assayed for their phytochemical constituents and in vitro antioxidant activities. The major constituents detected in the essential oil, as revealed by GC/MS analysis, contained mainly Z,Z-farnesyl acetone (11.04%), β-elemene (6.36%), n-octanal (5.98%), and spathulenol (4.58%). Each of the aqueous methanol (Sp-M) and butanol (Sp-B) extracts contained flavonoids, saponins, anthraquinone, and glycosides. Both extracts were evaluated for their total phenolic content (TPC), total flavonoid content (TFC), and their in vitro antioxidant activity, which were assayed using the DPPH radical scavenging activity and ABTS radical scavenging methods. Additionally, the two extracts were then subjected to LC-ESI-MS/MS for the qualitative determination of their secondary metabolite content, especially in flavonoids and phenolic compounds. The results showed that the Sp-B extract of S. peyronii had the highest contents of both phenolic compounds and flavonoids and showed high radical scavenging activity, as determined by the two assay methods, when compared with the Sp-M extract. The LC-ESI-MS/MS analysis resulted in the detection of 21 compounds, including 8 flavonoids, 6 phenolic acids, 6 iridoids, and 2 acids. Although the majority of compounds were detected in both extracts, it was noticed that scropolioside B, 6′-O-cinnamoylharpagide, isoferulic acid, and 6-O-methylcatapol were only detected in the Sp-M fraction.

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Section: Resultsmentioning

confidence: 99%

Scrophularia peyronii Post. from Jordan: Chemical Composition of Essential Oil and Phytochemical Profiling of Crude Extracts and Their In Vitro Antioxidant Activity

Al-Dalahmeh,

Almahmoud,

Al-Bataineh

et al. 2023

Life

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“…In a systematic review, Raeisi et al reported various types of herbs that are used to treat jaundice at different ages. The most important of these herbs are purgative manna, jujube, barley flour, Alhagi maurorum Medik, Fumaria officinalis, and chicory, which are used in the treatment of neonatal jaundice (24). A meta-analysis by Zeng et al performed on 2594 neonates (target group of 1307 and control group of 1287) in China showed that the use of Yin Zhi Huang oral liquid was more effective in treating jaundice than placebo (42).…”

Section: Discussionmentioning

confidence: 99%

“…Barley flour is used to treat neonatal jaundice in Lorestan, Iran. Some studies have also evaluated plants such as jujube, chicory, and orchid (23,24).…”

Section: Contextmentioning

confidence: 99%

Effect of Natural Products on Jaundice in Iranian Neonates

Fakhri

Farhadi

Mousavinasab

et al. 2019

Jundishapur J Nat Pharm Prod

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Context: Neonatal jaundice is the most common clinical problem in preterm and term neonates, and phototherapy is the most frequent treatment method for this condition. Researchers have long held that the use of natural products, especially medicinal plants, can reduce the incidence of neonatal jaundice, and in turn, the use of phototherapy in the treatment of neonatal jaundice in some countries including Iran. Objective: We aimed to carry out a systematic review on the effects of natural products on jaundice in Iranian neonates. Data Sources: Articles evaluating the effect of natural products on jaundice in Iranian neonates until the end of 2017 were searched using Google Scholar and IranMedex, SID, Magiran, IranDoc, Medlib, ScienceDirect, PubMed, Scopus, Cochrane, Embase, Web of Science, and Medline databases. Study Selection: Studies evaluating the effect of natural products on neonatal jaundice were included in the study. Studies were selected from the databases by screening titles, keywords and abstracts. Hence, all the articles which had the keywords in their titles, keywords or abstracts were selected. The inclusion criteria included: carrying out the study in Iran, being performed on neonates and using a natural product (herbal or non-herbal) to reduce neonatal jaundice. The articles that did not meet these criteria were excluded. Data Extraction: The ideal reporting items for systematic review and meta-analysis (PRISMA) checklist was used to evaluate the quality of the articles. Finally, a checklist was designed by the researchers to collect the data. The items of the checklist were the name of the first author of article, study objective, study setting, age, weight, number and gender of the neonates included, name, dose and frequency of the use of the natural product, route of delivery, and method of using the natural product (such as oral/nonoral). Results: The number of neonates enrolled in the 21 included studies was 2237. The effect of natural products on preventing neonatal jaundice was not statistically significant, but in some studies, the use of natural products in combination with phototherapy was found to be effective in the treatment of neonatal jaundice. Conclusions: The use of natural products for the prevention and treatment of neonatal jaundice requires further studies, but the usage of natural products such as medicinal plants like Cotoneaster with phototherapy could be possibly effective in reducing the duration of phototherapy and hospitalization.

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Cited by 2 publications

References 14 publications

Scrophularia peyronii Post. from Jordan: Chemical Composition of Essential Oil and Phytochemical Profiling of Crude Extracts and Their In Vitro Antioxidant Activity

Scrophularia peyronii Post. from Jordan: Chemical Composition of Essential Oil and Phytochemical Profiling of Crude Extracts and Their In Vitro Antioxidant Activity

Effect of Natural Products on Jaundice in Iranian Neonates

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