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Abstract

The United States Alzheimer's Association 2 reports 6.2 million Americans 65 years and older had AD in 2021. When we consider the probable undiagnosed AD and all-cause dementia population, there may be 10 million people in the USA with all-cause dementia. Nichols, Vas, Murray et al., 3 estimate that by 2050 the quantity of people globally with all-cause dementia will triple. Similarly, the number of all-cause dementia cases in the United States by 2050 would be 30 million.The World Health Organization 4 reports more than 55 million people worldwide have dementia. They report AD is the most common dementia, representing 2/3rds of all dementia cases. Earlystage dementia is often characterized by forgetfulness, losing track of time, or becoming lost in familiar places. Middle-stage dementia may include forgetting recent events and the names of people, confusion at home, increased difficulty with communication, needing assistance with personal care, wandering and repeated questioning. Late-stage dementia is characterized as being unaware of time and place, difficulty recognizing relatives and friends, requiring assistance for self-care and possibly aggressive behaviors.