Abstract:Background:The study aimed to optimize and validate a nano-particulate technology for the sustained release of perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor, using a box-behnken experimental methodology. Methods: The researcher used a Box-behnken experimental methodology to optimize the formulation and assess various characteristics such as particle size, zeta potential, surface shape, encapsulation efficiency and in vitro drug release. The nanoparticles characterization findings were … Show more
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