This chapter aims at presenting a concise picture of the research in Biomechanics developed by researchers of various disciplinary areas that refer to AIMETA. The research collectors are the international journal Meccanica, published by Springer, and the AIMETA congresses including publications of studies presented therein. This chapter is devoted to studies related to AIMETA activity and mainly refers to the topics from the above-mentioned sources. Final comments and future developments are outlined. Keywords Biomechanics • Biological tissues • Articular biomechanics • Medical devices • Biological fluid mechanics • Cardiovascular mechanics 1 Introduction, from Mechanics to Biomechanics Biomechanics is the science that studies the structure and function of biological systems using methods and knowledge of Mechanics. The birth of Biomechanics can be dated back to the first studies of Aristotle (384-322 BC) and later developed by Galen (129-210), Leonardo da Vinci (1452-1519), Galileo Galilei (1564-1642), and Giovanni Alfonso Borelli (1608-1679, up to a few further advancements through the nineteenth and twentieth centuries. It found in the last 50 years a rebirth of interests that became an exponential growth in the last 20 years. In the 50's of the past century, it was in fact considered a subject for