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Klimenko, S. K.; Stolbova, T. V.; Kulikova, K.; Shub, G. M.

doi:10.1023/a:1012751119701

Cited by 2 publications

(2 citation statements)

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“…More recently, Galkin et al . reported a series of (carboxyalkyl)dimethylsulfonium halides 20 which exhibited good antibacterial activity against S. aureus with poorer activity against Gram‐negative strains, including E. coli and P. aeruginosa (Figure 5, right) [44,45] . These reports presented early evidence of the promising antibacterial activity of the sulfonium moiety.…”

Section: Trivalent Sulfonium Compounds As Novel Antisepticsmentioning

confidence: 97%

“…In the early 2000s, Klimenko et al . reported examples of methylated thianes with both iodide [43] ( 19 a ) and argentate [44] ( 19 b ) anions (Figure 5, left). These compounds exhibited strong antibacterial activity against both Gram‐negative and Gram‐positive bacterial strains (MIC=25–50 μM).…”

Section: Trivalent Sulfonium Compounds As Novel Antisepticsmentioning

confidence: 99%

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Advancements in the Development of Non‐Nitrogen‐Based Amphiphilic Antiseptics to Overcome Pathogenic Bacterial Resistance

et al. 2020

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The prevalence of quaternary ammonium compounds (QACs) as common disinfecting agents for the past century has led bacteria to develop resistance to such compounds. Given the alarming increase in resistant strains, new strategies are required to combat this rise in resistance. Recent efforts to probe and combat bacterial resistance have focused on studies of multiQACs. Relatively unexplored, however, have been changes to the primary atom bearing positive charge in these antiseptics. Here we review the current state of the field of both phosphonium and sulfonium amphiphilic antiseptics, both of which hold promise as novel means to address bacterial resistance.

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Section: Trivalent Sulfonium Compounds As Novel Antisepticsmentioning

confidence: 97%

Section: Trivalent Sulfonium Compounds As Novel Antisepticsmentioning

confidence: 99%