A monolithic single-pole, fourteen-throw (SP14T) antenna switch module (ASM) with on-chip transmit filters is implemented in a 180nm silicon-on-insulator CMOS process for multi-mode multi-band cellular handsets. To ensure compatibility with control interfaces and multi-band linear operation, a mobile industry processor interface decoder, a positive voltage regulator, a negative voltage generator, and an asymmetric RF-core topology are incorporated. Moreover, an optimal on-chip filter matching method is introduced to achieve a fully integrated solution that enhances both harmonic performance and miniaturization. The SP14T ASM exhibits excellent insertion loss, isolation, linearity, and harmonic performance across different modes.