A 10-year study: Renal outcomes in patients with accelerated hypertension and renal dysfunction

Anitha, A; Babu, Kishore

doi:10.4103/ijn.ijn_332_19

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…Three patients died. 27 Eight percent of patients (8/100) in the retrospective study by Singh et al from Haryana had CKD and 24 had renal dysfunction overall. 9 Twelve% of patients admitted to the ICU for HTN-E (6/50) had CKD in a study from Maharashtra.…”

Section: Discussionmentioning

confidence: 98%

Burden and outcomes of chronic kidney disease in patients presenting with hypertensive crisis

Viswanathan

Yalavarthy

2023

Preprint

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Objectives To determine prevalence of chronic kidney disease (CKD) in patients presenting with hypertensive crises and to determine their 30-day outcomes with respect to blood pressure (BP), creatinine level, and mortality. Methods Patients admitted to the HTN-C were prospectively enrolled. Demographics, examinations, target organ damage (TOD), and investigations were recorded. Patients were classified as hypertensive emergency(HTN-E) or hypertensive urgent(HTN-U). TODs included cardiovascular (acute coronary syndromes and pulmonary edema), neurological (stroke, encephalopathy), ocular (retinal hemorrhage, papilledema), renal (acute kidney injury-AKI), and hematological (microangiopathic hemolytic anemia). The CKD burden was determined. BP, creatinine, and mortality were assessed at discharge and after 30 days. AKI was confirmed at follow-up, with a reduction in creatinine level of > 25%. Results 235/262 patients had HTN-E; patients were mostly male and middle-aged. The TOD with decreasing frequency was cardiovascular(53%), ocular(29%), neurological(26%), and AKI(24%). Patients with CKD were significantly younger, had hypertension with ≥ 2 drugs, and had a higher proportion of TOD. Patients with CKD had significantly higher BP and creatinine levels at discharge and at 30 days; the non-CKD group had a higher inpatient mortality rate and lower mortality at 30 days. Conclusions Specific markers of AKI in patients with underlying CKD are needed to prioritize care during hypertensive crises. Better community-level support in the form of physicians, nephrologists, and dialysis centers is required for timely assessment of the diagnosis and progression of CKD, recognition and treatment of AKI, control of blood pressure, and regular dialysis, which may reduce the load on emergency departments for hypertensive crises.

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Section: Discussionmentioning

confidence: 98%

Burden and outcomes of chronic kidney disease in patients presenting with hypertensive crisis

Viswanathan

Yalavarthy

2023

Preprint

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“…Uncontrolled hypertension was considered when the values of blood pressure were above ≥ 95th percentile based on age, sex, and height, in spite of receiving antihypertensive medications. Hypertensive encephalopathy is defined as acute brain dysfunction such as severe headache, changes in consciousness, seizure, and retinal hemorrhage induced by sustained severe hypertension (13).…”

Section: Methodsmentioning

confidence: 99%

Pattern of Renal and Urinary Tract Diseases Among Children Admitted to A General Ward Over One Year

Kotb

Yassin

Lotfi

et al. 2022

Pediatric Sciences Journal

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Background: Children with renal and urinary tract diseases may require admission in general pediatric wards. Aim of the work:To identify the pattern of renal and urinary tract diseases among children admitted to general pediatric ward and their associated morbidities and mortality. Methods: Retrospective analysis of files of children with confirmed diagnosis of renal and urinary tract diseases who were admitted to a general pediatric ward, at Children Hospital, Cairo University. Results: During 12 months, 142 patients with renal or urinary tract disease were admitted to our pediatric general ward. Of them 97 (68.3%) were boys and 45 (31.7%) were girls. Their mean age was 5.1 ± 3.89 years. Of them 121 (85.2%) had isolated renal disease and 21 (14.8%) had renal affection as a part of systemic diseases. The most common diseases among those with isolated renal disease, were glomerular diseases (62 patients, 51.2%), followed by congenital anomalies of the kidney and urinary tract (33 patients, 27.3%). Different types of infection were the main cause for admission among 78 (54.9%) children. Thirty four patients (23.9%) underwent renal replacement therapy, and 26 patients suffered from poor outcome. Conclusion:Pediatricians should have the knowledge of the different presentations of renal disease in children and be trained for timely referral to the pediatric nephrologists and/or urologist. Renal diseases should be suspected in those with diseases of other systems. Infections are the commonest renal indication of admission in the general pediatric ward.

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A 10-year study: Renal outcomes in patients with accelerated hypertension and renal dysfunction

Cited by 2 publications

References 24 publications

Burden and outcomes of chronic kidney disease in patients presenting with hypertensive crisis

Burden and outcomes of chronic kidney disease in patients presenting with hypertensive crisis

Pattern of Renal and Urinary Tract Diseases Among Children Admitted to A General Ward Over One Year

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