A 15-Month-Old Boy With a Rash on His Hands and Feet

Lloyd, Elizabeth C; Gross, Elise; Diamond, Rebekah; Cobb, Ashley; Allen, Brittany; Liu, Ying; Dawid, Suzanne; Tribble, Alison C.

doi:10.1093/jpids/piy097

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…However, there are a few studies recently published. As in the US at the University of Michigan, reported an unusual presentation of a case of a 15-month-old boy with intermittent fever, rash, and refusal to bear weight which diagnosed by isolated anaerobic joint fluid culture showed Streptobacillus moniliformis [8]. Also, it could be fatal as a case reported from San Diego Health and Human…”

Section: Discussionmentioning

confidence: 97%

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Rat Bite in A 55-Days Old Girl Presenting Without Fever: A Case Report

AlGoraini

Alghamdi

2019

AJBSR

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Section: Discussionmentioning

confidence: 97%

“…It is an unusual age presentation of a rat bite comes without fever. There are a few cases has been reported in children [3][4][5][6][7][8][9] and adults as well [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Rat Bite in A 55-Days Old Girl Presenting Without Fever: A Case Report

AlGoraini

Alghamdi

2019

AJBSR

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Septic arthritis complicating Streptobacillus moniliformis rat bite fever: a case report and review of its pathophysiology and diagnosis

Giraudon,

Larranaga Lapique,

Wallemacq

et al. 2024

Front. Med.

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Rat bite fever is characterized by a clinical triad of symptoms, fever, rash and arthritis. It is transmitted by rodents and mainly due to infection by Streptobacillus moniliformis, a fastidious bacterium carried by Rattus norvegicus. This case report presents the case of a patient who developed septic arthritis and fever after a wild rat bite, with subsequent isolation of S. moniliformis from the joint fluid. Upon reviewing 45 other published case reports of S. moniliformis osteoarticular infections following contact with either a rat or its secretions, it was firstly observed that the rat bite fever clinical triad was incomplete in over half of the cases, mainly because rash was infrequently observed among adult patients. Secondly, the clinical presentation of rat bite fever is quite non-specific and rodent exposure is not mentioned by patients in a third of cases upon admission. Altogether, diagnosing rat bite fever is a significant clinical challenge suggesting that it might be significantly underdiagnosed. In addition to these clinical aspects, no evidence was found supporting immunological mechanisms, as suggested in some literature. Instead, when excluding five improperly performed cultures, S. moniliformis was cultured in 25 reported cases and identified twice by direct PCR sequencing amounting to a detection rate of 90% (n = 27/30) on joint fluids. Cultures should be performed in medium containing yeast extract, complete peptic digest of animal tissue and at least 5% blood. Knowing that S. moniliformis is very sensitive to many antibiotics thereby making the culture negative, direct 16S rRNA gene sequencing on joint fluid is an alternative method in the case of clinical and cytological evidence of osteoarticular infections with sterile culture of joint fluid.

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A 15-Month-Old Boy With a Rash on His Hands and Feet

Cited by 2 publications

References 5 publications

Rat Bite in A 55-Days Old Girl Presenting Without Fever: A Case Report

Rat Bite in A 55-Days Old Girl Presenting Without Fever: A Case Report

Septic arthritis complicating Streptobacillus moniliformis rat bite fever: a case report and review of its pathophysiology and diagnosis

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