A 16-year-old Girl With Pain and Swelling in the Medial Clavicle

An 11-year-old child presented to the emergency department in 2005 with episodes of pain in his right clavicle. No history of trauma was noted and he was systemically well with no clinical signs of acute inflammation. He was extensively investigated and a diagnosis of fibrous dysplasia of the right clavicle was reached on histology. He developed periodic relapses of pain in the clavicle. He has been followed up since 2005, his most recent follow-up being in November 2011. The clinical dilemma of fibrous dysplasia versus chronic osteomyelitis is illustrated by highlighting this case.

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“…A sclerotic rim of bone is usually seen around these lesions 2. Pathological fracture is well described in larger lesions 2…”

Section: Discussionmentioning

confidence: 99%

“…Radiographically, they are multiloculated lesions 2. A sclerotic rim of bone is usually seen around these lesions 2.…”

Section: Discussionmentioning

confidence: 99%

A dilemma of fibrous dysplasia versus chronic osteomyelitis of the clavicle

Weerasuriya

Nashi²,

Morgan³

et al. 2012

Case Reports

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“…Wester et al [ 5 ] reported 61 cases of LCH occurring in adults, with only 6 % involving the clavicle. A solitary lesion in the clavicle is extremely rare, and only 12 cases have been reported to date [ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 ].…”

Section: Discussionmentioning

confidence: 99%

Langerhans Cell Histiocytosis of the Clavicle in an Adult: A Case Report and Review of the Literature

Udaka

Susa

Kikuta³

et al. 2015

Case Rep Oncol

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Langerhans cell histiocytosis (LCH) usually occurs in children under the age of 10 years with a predilection for the skull, spine, rib and humerus. Solitary LCH occurring in an adult clavicle is uncommon with limited reports to date. The lesion in our patient was curetted with the intent to make a diagnosis, which subsequently lead to the remission of the symptom and the disease. At the final follow-up after 1 year, no local recurrence or metastasis is observed.

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“…MRI findings of soft tissue involvement or areas of localized hemorrhagic necrosis of lesion are characteristic features of Ewing sarcoma [ 6 ]. Osteomyelitis can present as a tender, firm swelling on examination, and as an osteolytic lesion with periosteal reaction on imaging studies [ 6 , 9 ]. Laboratory values including ESR and CRP are typically elevated in osteomyelitis.…”

Section: Discussionmentioning

confidence: 99%

Langerhans Cell Histiocytosis of the Clavicle in a 13-Year-Old Boy

Parikh

Desai

Gupta

et al. 2014

Case Reports in Orthopedics

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Langerhans Cell Histiocytosis (LCH) is a rare neoplasm characterized by abnormal proliferation of histiocytic cells. In this case report, we describe a unique case of a 13-year-old boy who presented to the clinic with an insidious onset of mid-clavicular pain. The provisional radiologic diagnosis of Langerhans Cell Histiocytosis of the clavicle was confirmed by an incisional biopsy of the left mid-clavicle lesion. The patient's lesion was treated by curettage, bone grafting, and internal fixation, due to the presence of pathologic fracture. At the 2-year followup, the patient was asymptomatic, and the lesion showed complete resolution without recurrence. The case report highlights the characteristic features of Langerhans Cell Histiocytosis in an unusual location, the knowledge of which would help avoid delayed or missed diagnosis in the future.

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A 16-year-old Girl With Pain and Swelling in the Medial Clavicle

Cited by 8 publications

References 11 publications

A dilemma of fibrous dysplasia versus chronic osteomyelitis of the clavicle

A dilemma of fibrous dysplasia versus chronic osteomyelitis of the clavicle

Langerhans Cell Histiocytosis of the Clavicle in an Adult: A Case Report and Review of the Literature

Langerhans Cell Histiocytosis of the Clavicle in a 13-Year-Old Boy

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