A 300 Hz TEA CO2 Laser

Natural Product Chemistry for Nitric Oxide Based Therapeutics

“…To demonstrate the safety and efficacy of this approach a number of randomized controlled clinical trials have been conducted. In subjects over the age of 40 with two or more cardiovascular risk factors, taking the NO lozenge twice daily for 30 days leads to a significant reduction in triglycerides, reduction in inflammation and lowering of blood pressure . In another double‐blinded, randomized, placebo controlled study of subjects with pre‐hypertension (BP 120–139 mmg Hg systolic and 80–89 mm Hg diastolic), taking the lozenge twice daily for 30 days reduced systolic blood pressure by 12 mm Hg and reduced diastolic blood pressure by 6 mm Hg.…”

“…Our screening of natural product libraries found an extract of hawthorne berry to contain a very stable oxygen independent nitrite reductase. Interestingly when combined with a specific extract of beet root enhanced the activity even more . In considering safety first, an important component when delivering nitrite or NO is the formation of low molecular weight N‐nitrosamines.…”