A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit

Tekin, Recep; Dal, Tuba; Pirinççioğlu, Habibe; Oygucu, Seyhan Erişir

doi:10.1016/j.pedneo.2013.03.011

Cited by 41 publications

(46 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In our hospital, the detection of multi-resistant A. baumanii in ICU-acquired infections resulted in increasing the use of colistin and conseguently a significant increase in colistin resistance was detected. Increasing infection control measures by improving isolation conditions, especially in our patients with RTIs, which were frequently infected with multi-drug resistant A. baumanii, may lead to a decrease in colistin resistance rates as has been demonstrated by other studies [20,21]. In addition, we found a significant decrease in the rate of detection of all gram negative and gram positive bacteria as pathogens in BSI and UTI (Table 5, 6).…”

Section: Discussionsupporting

confidence: 73%

Increased colistin resistance of Acinetobacter species in intensive care unit-acquired infections in a tertiary care hospital

Gecgel¹,

Demir²

2017

int. arab. j antimicrob. agents

View full text Add to dashboard Cite

Background: The aim of our study was to evaluate the antimicrobial resistance rates among pathogen microorganisms especially colistin resistant rates of Acinetobacter baumannii in intensive care unit (ICU)-acquired infections and to determine infection-specific correct treatment strategies. Methods:The data of adult and newborn infant patients diagnosed with ICU-acquired infection in a tertiary education and research hospital in Bursa in 2014 and 2016 were analyzed, retrospectively.

show abstract

Section: Discussionsupporting

confidence: 73%

Increased colistin resistance of Acinetobacter species in intensive care unit-acquired infections in a tertiary care hospital

Gecgel¹,

Demir²

2017

int. arab. j antimicrob. agents

View full text Add to dashboard Cite

show abstract

“…An Italian study identified 6.6% children with VAP among 451 on mechanical ventilation [25], and a mixed PICU in Australia identified 6.7% children with VAP among 269 on mechanical ventilation [26]. VAP is also common in the NICU and proportions between 6.8% and 57.0% of HAIs have been reported [34,[60][61][62][63][64][65][66]. A Spanish study identified VAP in 9.1% of 198 neonates on mechanical ventilation [67].…”

Section: Epidemiologymentioning

confidence: 99%

Ventilator-associated pneumonia in neonates, infants and children

Aelami

Lotfi

Zingg

2014

Antimicrob Resist Infect Control

View full text Add to dashboard Cite

Ventilator-associated pneumonia (VAP) is relatively common in mechanically-ventilated children, but there is a wide variation in reported VAP rates, depending on settings and geographical regions. Surveillance definitions in children are challenging. Although these are provided by the German nosocomial infection surveillance system and an independent Dutch group, the combination of clinical and radiologic signs leaves room for interpretation. Of note, the United States Centers for Disease Prevention and Control guidelines do not offer algorithms for neonates. Despite the fact that most experts agree on the low sensitivity and specificity of existing definitions, little has changed over the past years. However, the number of studies reporting on VAP prevention programs has increased in recent years. Single interventions, such as chlorhexidine mouth wash or stress ulcer prophylaxis, were not effective. Successful prevention programs combined multiple interventions, such as hand hygiene, glove and gown use for endotracheal tube manipulation, backrest elevation, oral care with chlorhexidine, stress ulcer prophylaxis, cuff pressure maintenance where appropriate, use of orogastric tubes, avoidance of gastric overdistension, and elimination of non-essential tracheal suction. These multimodal strategies have proved to be successful among neonates, infants, and children. Importantly, they are applicable in high-as well as in low-and middle-income countries. This review provides an update of VAP incidence rates and summarizes current knowledge on its epidemiology, risk factors, surveillance definitions, and prevention programs in the pediatric setting.

show abstract

“…These bacteria are common in adult and paediatric intensive care units (ICUs) [3,4] and have been associated with increased mortality rates and longer length of stay [5]. Such issues frequently involve patients with acquired brain injury (ABI) [6], who present several risk factors such as mechanical ventilation, longlasting impairment of consciousness and having undergone surgery [7,8].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of respiratory colonisations and related antibiotic resistances among paediatric tracheostomised patients of a long-term rehabilitation centre in Italy

Pozzi¹,

Pellegrino²,

Galbiati³

et al. 2014

Eur J Clin Microbiol Infect Dis

View full text Add to dashboard Cite

Patients with brain injury are prone to bacterial colonisations because of mechanical ventilation during intensive care and the long-term retention of tracheostomical tubes during rehabilitation. Reduced levels of isolation, typical of rehabilitation, could also contribute to propagate colonisations. We evaluated the presence of bacteria through different stages of healthcare, their antibiotic resistances and their clinical impact in a rehabilitation setting. This retrospective study included all tracheostomised patients referred to the paediatric brain injury unit of the Scientific Institute IRCCS E. Medea (Italy) over a six-year period. Data were collected from antibiograms regarding the presence of bacterial species and antibiotic resistances; clinical data were collected from medical records. Antibiograms revealed bacteria and antibiotic resistances typical of intensive care, while prevalence patterns were characteristic for each species (P. aeruginosa and S. aureus prevailing in the acute setting, K. pneumoniae, A. baumannii and others in rehabilitation). Despite very frequent antibiotic resistances, consistent with Italian averages, we observed a limited clinical impact for these colonisations. We analysed risk factors correlating to the development of respiratory symptoms and found a role for the acute clinical course after brain injury (having undergone neurosurgery; duration of intensive care stay) as well as for rehabilitation (duration of coma). Our data suggest that, in a long-term perspective, an appropriate balance is yet to be found between patient isolation and social interactions, to control respiratory colonisations and antibiotic resistances without compromising rehabilitation. They also suggest that regular containment measures should be complemented by thorough training to non-medic personnel and parents alike.

show abstract

A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit

Abstract: Device-associated nosocomial infections was a particularly important problem in NICU. Close monitoring will decrease the rates of device-related nosocomial infections.

Cited by 41 publications

References 23 publications

Increased colistin resistance of Acinetobacter species in intensive care unit-acquired infections in a tertiary care hospital

Increased colistin resistance of Acinetobacter species in intensive care unit-acquired infections in a tertiary care hospital

Ventilator-associated pneumonia in neonates, infants and children

Prevalence of respiratory colonisations and related antibiotic resistances among paediatric tracheostomised patients of a long-term rehabilitation centre in Italy

Contact Info

Product

Resources

About