A 5.8 GHz Ophthalmic Microwave Applicator for Treatment of Choroidal Melanoma

Finger, Paul T.; Packer, Samuel; Svitra, Paul P.; Paglione, R.W.; Albert, Daniel M.; Chess, Jeremy

doi:10.1109/mwsym.1983.1130849

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…The etching process selectively left a 2 mm free margin between the copper disc and the edge of the antenna (Fig 1). 20 26 A short length of flexible silicone-covered coaxial cable AS 450-3650 SR (Cooner Wire, Chatsworth, CA, USA) was used to direct the microwave energy from the microwave generator/ amplifier to the patch antenna. The silicone coating was removed at one end which exposed the centre conductor.…”

Section: Microwave Thermotherapymentioning

confidence: 99%

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Microwave plaque thermoradiotherapy for choroidal melanoma.

Finger

1992

British Journal of Ophthalmology

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Microwave thermoradiotherapy was used as a primary treatment for 44 patients with choroidal melanoma. An episcleral dishshaped microwave antenna was placed beneath the tumour at the time of plaque brachytherapy. While temperatures were measured at the sclera, the tumour's apex was targeted to receive a minimum of 42°C for 45 minutes. In addition, the patients received full or reduced doses of plaque radiotherapy. No patients have been lost to foliow-up. Two eyes have been enucleated: one for rubeotic glaucoma, and one for uveitic glaucoma. Though six patients have died, only one death was due to metastatic choroidal melanoma (39 months after treatment). Clinical observations suggest that the addition of microwave heating to plaque radiation therapy of choroidal melanoma has been weli tolerated. There has been a 97-7% local control rate (with a mean follow-up of 22.2 months). We have reduced the minimum tumour radiation dose (apex dose) to levels used for thermoradiotherapy of cutaneous melanomas (50 Gy/5000 rad). Within the range of this foliow-up period no adverse effects which might preclude the use of this microwave heat delivery system for treatment of choroidal melanoma have been noted.

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Section: Microwave Thermotherapymentioning

confidence: 99%

“…1-3 Though no significant scleral damage has been noted in this series, the possibility of such damage (as noted in preclinical studies) was discussed. 20 The patients had a complete eye examination prior to treatment. After refraction, pupillary, ocular motor, and slit-lamp examinations were performed.…”

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confidence: 99%