A 5-year registry of mechanically ventilated patients comprising epidemiology, initial settings, and clinical outcome

Nassar, Yasser; Magdy, Mena; Hamed, Lamia; Algohary, Tarek

doi:10.4103/ejcdt.ejcdt_34_18

Cited by 5 publications

(15 citation statements)

References 2 publications

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“…Similarly, Tobi et al found volume-controlled ventilation (VCV) as the main (61.8%) initial ventilation strategy. 6 On the other hand, the study conducted in India and Brazil indicates the predominant mode of initial ventilation (66% and 73%) was the PCV, and in Benin teaching hospital, Nigeria the preferred mode of ventilation was SIMV (52.3%) which is different from our study. 5 , 15 , 17 The selection of initial ventilation strategy can be varying based on individual preferences and needs.…”

Section: Discussioncontrasting

confidence: 99%

“…This finding is in line with the finding by Nassar et al in which 14.8% of the patients developed VAP as a major complication. 6 However, the report from Berhe et al shows a higher VAP (27.6%) rate than our study. 11 This might be due to better care in our study setting.…”

Section: Discussioncontrasting

confidence: 82%

“… 19 The report from Nassar et al also showed that the duration of mechanical ventilation was 6±10 days, which is slightly similar to our study. 6 However, the study from southern Brazil and Nigeria showed a higher mean duration of stay on mechanical ventilation which is 9.3 days and 12.3 days, respectively. 15 , 17 The discrepancy in ventilator stay might be attributed to the late admission of patients.…”

Section: Discussionmentioning

confidence: 87%

“…In those studies, the preferred method of weaning were T-tube and PS-CPAP, respectively. 6 , 9 The variation in the findings could be attributed to the preference of the physicians and the patient’s tolerance for both methods.…”

Section: Discussionmentioning

confidence: 99%

“…Patient management and pre‑mechanical ventilation factors were found to be independently associated with increased mortality. 5 , 6 …”

Section: Introductionmentioning

confidence: 99%

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Characteristics and Outcomes of Mechanically Ventilated Patients at Adult ICU of Selected Public Hospitals in Addis Ababa, Ethiopia

Alemayehu¹,

Azazh²,

Hussien³

et al. 2022

OAEM

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Introduction Mechanical ventilation is the primary method of supporting organ function for patients admitted to intensive care units (ICU). The information on the characteristics and outcomes of patients requiring mechanical ventilation is essential to understanding the causes of mortality among mechanically ventilated patients. However, the available literature in developing countries, including Ethiopia, is limited. Objective The objective of this study was to assess the characteristics and outcomes of mechanically ventilated patients in adult intensive care units in selected public hospitals, in Addis Ababa, Ethiopia, from 2019 to 2020. Methods An institutional-based cross-sectional study design was employed. All adult patients who were mechanically ventilated and admitted to ICU for at least 24 hours between July 2019 and July 2020 were included in the study. The collected data were evaluated with SPSS version 26 software. Multiple logistic regression models were used to indicate the association between dependent and independent variables. The variables, which have an independent association with poor outcomes, were identified with a p-value less than 0.05. Results Of 180 mechanically ventilated patients, 98(54.4%) were male. The main reason for ventilation was respiratory failure. The mean duration of stay on the ventilator was 7.09± 6.06, and the mortality rate in mechanically ventilated patients was 41.7%. The mortality rate was higher in patients with cardiac diseases 43(57.70%). Inotropic use, not taking sedation, and length of stay on a mechanical ventilator were independently associated with mortality. Conclusion The mortality rate of mechanically ventilated patients in the selected public hospitals was high. The clinicians must strive to balance the necessity and benefit of sedation use with the potential to negatively affect the patient outcome. In addition, the risk:benefit assessment of ventilation must be done for all patients requiring ventilator support.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussioncontrasting

confidence: 82%

Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

“…Patient management and pre‑mechanical ventilation factors were found to be independently associated with increased mortality. 5 , 6 …”

Section: Introductionmentioning

confidence: 99%

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Characteristics and Outcomes of Mechanically Ventilated Patients at Adult ICU of Selected Public Hospitals in Addis Ababa, Ethiopia

Alemayehu¹,

Azazh²,

Hussien³

et al. 2022

OAEM

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Outcomes of Patients on Mechanical Ventilation among Adult Intensive Care Units of Tikur Anbesa Specialized Hospital, Addis Ababa , Ethiopia

Tsegay,

Teklu,

Debebe

et al. 2023

Preprint

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Background Mechanical ventilation is a supportive treatment for patients who are unable to maintain adequate oxygenation and/or removal of carbon dioxide. One of the most common indications of admission to the intensive care unit is the need for the ventilator support. Patients admitted to intensive care units who need mechanical ventilation had been higher mortality rates than those who do not require respiratory support. The objective of the study was to assess the clinical profile and outcomes of patients on mechanical ventilation among adult intensive care units of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, 2020. Methods Retrospective cross-sectional study was employed using a principal investigator developed (PI) data extraction form. We reviewed retrospectively a one-year medical record of ventilated patient from September 1, 2018- August 30, 2019. Data were analyzed using statistical package for social science (SPSS) version 25. Description of median frequency and standard deviation (SD) on each variable were calculated. Multivarte logistic regression was assessed to association between dependent and independent variable. Results There were 693 patients admitted to AICU over the one year and 348(50.2%) were mechanically ventilated. The main source for admission was Adult emergency and operation room with same percent (37.6%). The main reason for ICU admission was respiratory (55.2%). The predominant indication of mechanical ventilation was respiratory failure (41.9%), neurological failure (36.7%) and sepsis (11.4%). Volume control ventilation was the most common initial mode of ventilation used. In multivariable regression analysis being medical diagnosis patients, multi organ dysfunction syndrome and sedation used were statistically positively associated with mortality at p-value of less than 0.05 with CI 95%. Conclusions The mortality rate of Adult patients on mechanical ventilation in Tikur Anbessa specialized hospital was high. This high mortality rate suggesting an urgent need for extensive improvement in protocols for ICU set up.

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Mortality and its associated factors among mechanically ventilated adult patients in the intensive care units of referral hospitals in Northwest Amhara, Ethiopia, 2023

Tadesse,

Tilahun,

Yesuf

et al. 2024

Front. Med.

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BackgroundWorldwide, nearly half of the patients admitted to intensive care units require ventilatory support. Despite advances in intensive care unit patient management and mechanical ventilator utilization, the odds of mortality among mechanically ventilated patients are higher in resource-limited settings. Little is known about the mortality of patients on mechanical ventilation outside the capital of Ethiopia. This study aimed to assess mortality and its associated factors among mechanically ventilated adult patients in intensive care units.MethodAn institutional-based cross-sectional study was conducted on mechanically ventilated patients in intensive care units from 1 February 2020 to 1 March 2023. A simple random sampling technique was used to select 434 patients’ charts. A data extraction tool designed on the Kobo toolbox, a smartphone data collection platform, was used to collect the data. The data were exported into Microsoft Excel 2019 and then into Stata 17 for data management and analysis. Descriptive statistics were used to summarize the characteristics of the study participants. A bivariable logistic regression was conducted, and variables with p ≤ 0.20 were recruited for multivariable analysis. Statistical significance was declared at p < 0.05, and the strength of associations was summarized using an adjusted odds ratio with 95% confidence intervals.ResultA total of 404 charts of mechanically ventilated patients were included, with a completeness rate of 93.1%. The overall proportion of mortality was 62.87%, with a 95% CI of (58.16–67.58). In the multivariable logistic regression, age 41–70 years (AOR: 4.28, 95% CI: 1.89–9.62), sepsis (AOR: 2.43, 95% CI: 1.08–5.46), reintubation (AOR: 2.76, 95% CI: 1.06–7.21), and sedation use (AOR: 0.41, 95% CI: 0.18–0.98) were found to be significant factors associated with the mortality of mechanically ventilated patients in the intensive care unit.ConclusionThe magnitude of mortality among mechanically ventilated patients was high. Factors associated with increased odds of death were advanced age, sepsis, and reintubation. However, sedation use was a factor associated with decreased mortality. Healthcare professionals in intensive care units should pay special attention to patients with sepsis, those requiring reintubation, those undergoing sedation, and those who are of advanced age.

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A 5-year registry of mechanically ventilated patients comprising epidemiology, initial settings, and clinical outcome

Cited by 5 publications

References 2 publications

Characteristics and Outcomes of Mechanically Ventilated Patients at Adult ICU of Selected Public Hospitals in Addis Ababa, Ethiopia

Characteristics and Outcomes of Mechanically Ventilated Patients at Adult ICU of Selected Public Hospitals in Addis Ababa, Ethiopia

Outcomes of Patients on Mechanical Ventilation among Adult Intensive Care Units of Tikur Anbesa Specialized Hospital, Addis Ababa , Ethiopia

Mortality and its associated factors among mechanically ventilated adult patients in the intensive care units of referral hospitals in Northwest Amhara, Ethiopia, 2023

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