A 6-month study of the effects of 0.3% triclosan/copolymer dentifrice on dental implants

Sreenivasan, Prem K.; Vered, Yuval; Zini, Avi; Mann, Jonathan; Kolog, Hilla; Steinberg, Doron; Zambon, Joseph J.; Haraszthy, Violet I.; Silva, Maike P. da; Vizio, William De

doi:10.1111/j.1600-051x.2010.01617.x

Cited by 43 publications

(65 citation statements)

References 26 publications

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“…Four articles presented with short follow up with less than 6 months [10-13], two articles were retrospective in design [6,14], one investigation was a review study [15], three articles employed the same study population than other included investigations in the present analysis [16-18], and 1 investigation presented with unclear and incomplete data [19]. …”

Section: Resultsmentioning

confidence: 99%

Non-Surgical Therapy for Peri-Implant Diseases: a Systematic Review

Amo¹,

Yu²,

Wang

2016

JOMR

137

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ObjectivesThe purpose of this paper was to systematically evaluate the effectiveness of non-surgical therapy for the treatment of peri-implant diseases including both, mucositis and peri-implantitis lesions.Material and MethodsAn electronic search in two different databases was performed including MEDLINE (PubMed) and EMBASE from 2011 to 2016. Human studies reporting non-surgical treatment of peri-implant mucositis and peri-implantitis with more than 10 implants and at least 6 months follow up published in English language were evaluated. A systematic review was performed to evaluate the effectiveness of the different methods of decontamination employed in the included investigations. Risk of bias assessment was elaborated for included investigations.ResultsTwenty-five articles were identified of which 14 were further evaluated and included in the analysis. Due to significant heterogeneity in between included studies, a meta-analysis could not be performed. Instead, a systematic descriptive review was performed. Included investigations reported the used of different methods for implant decontamination, including self-performed cleaning techniques, and professionally delivered treatment such as laser, photodynamic therapy, supra-/sub-mucosal mechanical debridement, and air-abrasive devices. Follow-up periods ranged from 6 to 60 months.ConclusionsNon-surgical treatment for peri-implant mucositis seems to be effective while modest and not-predictable outcomes are expected for peri-implantitis lesions. Limitations include different peri-implant diseases definitions, treatment approaches, as well as different implant designs/surfaces and defect characteristics.

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Section: Resultsmentioning

confidence: 99%

Non-Surgical Therapy for Peri-Implant Diseases: a Systematic Review

Amo¹,

Yu²,

Wang

2016

JOMR

137

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“…), one study excluded patients with generalized moderate‐to‐severe chronic periodontitis (Sreenivasan et al. ), one study included periodontally healthy patients (Felo et al. ) and one publication did not report the periodontal conditions (Truhlar et al.…”

Section: Resultsmentioning

confidence: 99%

Efficacy of patient‐administered mechanical and/or chemical plaque control protocols in the management of peri‐implant mucositis. A systematic review

Salvi

Ramseier

2015

J Clinic Periodontology

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Aim: To systematically assess the efficacy of patient-administered mechanical and/or chemical plaque control protocols in the management of peri-implant mucositis (PM). Material and Methods: Randomized (RCTs) and Controlled Clinical Trials (CCTs) were identified through an electronic search of three databases complemented by manual search. Identification, screening, eligibility and inclusion of studies was performed independently by two reviewers. Studies without professional intervention or with only mechanical debridement professionally administered were included. Quality assessment was performed by means of the Cochrane Collaboration's tool for assessing risk of bias. Results: Eleven RCTs with a follow-up from 3 to 24 months were included. Definition of PM was lacking or heterogeneously reported. Complete resolution of PM was not achieved in any study. One study reported 38% of patients with complete resolution of PM. Surrogate end-point outcomes of PM therapy were often reported. The choice of control interventions showed great variability. The efficacy of powered toothbrushes, a triclosan-containing toothpaste and adjunctive antiseptics remains to be established. High quality of methods and reporting was found in four studies. Conclusions: Professionally-and patient-administered mechanical plaque control alone should be considered the standard of care in the management of PM. Therapy of PM is a prerequisite for the prevention of peri-implantitis.

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“…The 0.3% triclosan, 2% copolymer, 0.243% sodium fluoride dentifrice reduces dental plaque and plaque-associated gingival bleeding around teeth and also around dental implants [16]. Gingival bleeding is a key sign of periodontal disease, especially plaque-associated gingivitis, but gingival bleeding can also be a sign of more serious forms of periodontal disease such as periodontitis.…”

Section: Resultsmentioning

confidence: 99%

Community-level assessment of dental plaque bacteria susceptibility to triclosan over 19 years

2014

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BackgroundTriclosan is a broad-spectrum antimicrobial agent used in toothpaste to reduce dental plaque, gingivitis and oral malodor. This community-level assessment evaluated the susceptibility of dental plaque bacteria to triclosan in samples collected over 19 years.MethodsA total of 155 dental plaque samples were collected at eleven different times over 19 years from 58 adults using 0.3% triclosan, 2% copolymer, 0.243% sodium fluoride toothpaste and from 97 adults using toothpaste without triclosan. These included samples from 21 subjects who used triclosan toothpaste for at least five years and samples from 20 control subjects. The samples were cultured on media containing 0, 7.5 or 25 μg/ml triclosan. Descriptive statistics and p values were computed and a linear regression model and the runs test were used to examine susceptibility over time.ResultsGrowth inhibition averaged 99.451% (91.209 - 99.830%) on media containing 7.5 μg/ml triclosan and 99.989% (99.670 - 100%) on media containing 25 μg/ml triclosan. There was no change in microbial susceptibility to triclosan over time discernible by regression analysis or the runs test in plaque samples taken over 19 years including samples from subjects using a triclosan-containing dentifrice for at least five years.ConclusionsThis community-level assessment of microbial susceptibility to triclosan among supragingival plaque bacteria is consistent with the long-term safety of a 0.3% triclosan, 2% copolymer, 0.243% sodium fluoride dentifrice.

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A 6-month study of the effects of 0.3% triclosan/copolymer dentifrice on dental implants

Abstract: Twice daily use of a triclosan/copolymer dentifrice may enhance dental implant maintenance by reducing dental plaque and GI.

Cited by 43 publications

References 26 publications

Non-Surgical Therapy for Peri-Implant Diseases: a Systematic Review

Non-Surgical Therapy for Peri-Implant Diseases: a Systematic Review

Efficacy of patient‐administered mechanical and/or chemical plaque control protocols in the management of peri‐implant mucositis. A systematic review

Community-level assessment of dental plaque bacteria susceptibility to triclosan over 19 years

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