In the teaching of Chemistry it is notorious that the presence of mathematical calculations, memorization of formulas and symbols, hinder student learning. Thus, this research seeks to analyze the interdisciplinary and contextualized approaches to the contents of General Chemistry, in textbooks of Higher Education, based on the guidelines of the NCP's. The research is descriptive, case study type, with the voluntary participation of 29 students from IFPI. A diagnostic evaluation is applied to the participants, followed by a qualitative analysis of the contents based on two bibliographies present in the General Chemistry subject plan. The theoretical framework brings an argumentative approach about the application of the textbook, the contextualized and interdisciplinary teaching, providing a theoretical basis for the development of the work. It is observed that most students feel difficulties in the contents of Chemical Kinetics and Electrochemistry, despite its contextualization, the latter addresses few applications. Moreover,it is noted the importance of these approaches for a more significant, concrete learning and a better teaching and learning of students, making them increasingly active and responsible for their own training.