A “Bad” case of Tako–Tsubo syndrome

Ieva, Riccardo; Correale, Michele

doi:10.1007/s11239-008-0289-8

Cited by 14 publications

(5 citation statements)

References 9 publications

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“…This can lead to left ventricular rupture. Although our patient had no flow acceleration in left ventricular outflow tract contrary to previous cases of increased left ventricular outflow tract gradient,78 these can be attributed to our echocardiographic assessment after the development of cardiac rupture.…”

Section: Discussioncontrasting

confidence: 86%

Rupture of Right Ventricular Free Wall Following Ventricular Septal Rupture in Takotsubo Cardiomyopathy with Right Ventricular Involvement

et al. 2017

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Most patients diagnosed with takotsubo cardiomyopathies are expected to almost completely recover, and their prognosis is excellent. However, complications can occur in the acute phase. We present a case of a woman with takotsubo cardiomyopathy with right ventricular involvement who developed a rupture of the right ventricular free wall following ventricular septal rupture, as a consequence of an acute increase in right ventricular afterload by left-to-right shunt. Our case report illustrates that takotsubo cardiomyopathy can be life threatening in the acute phase. Ventricular septal rupture in biventricular takotsubo cardiomyopathy may be a harbinger of cardiac tamponade by right ventricular rupture.

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Section: Discussioncontrasting

confidence: 86%

Rupture of Right Ventricular Free Wall Following Ventricular Septal Rupture in Takotsubo Cardiomyopathy with Right Ventricular Involvement

et al. 2017

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“…LVOT gradients were available for 7 TSC rupture patients and for 6 controls. Three patients in CR group and 1 in the control group had elevated LVOT gradient (125 mm Hg, Ishida et al 15 13 mm Hg in Ieva et al 16 70 mm Hg in our case, and 25 mm Hg in Metzl et al 17 A 2-way tabulation suggests rupture to be frequent, up to 75% in patients with gradient compared to 44% in patients without gradient (P = 0.31).…”

Section: Discussionmentioning

confidence: 46%

Cardiac Rupture in Takotsubo Cardiomyopathy: A Systematic Review

Kumar

Kaushik

Nautiyal

et al. 2011

Clinical Cardiology

112

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Background: Takotsubo cardiomyopathy (TSC) and its complications, such as cardiac rupture (CR), are increasingly being reported in the literature. CR is associated with rapid clinical decline and is uniformly fatal if not surgically repaired. To identify patients who developed CR we performed an analysis of all available indexed cases in the literature and compared them with a control group of patients with TSC without rupture. Hypothesis: Takotsubo cardiomyopathy patients with cardiac rupture do not differ significantly from those without rupture. Methods: MEDLINE (2009) was searched for all TSC case reports with CR. Eleven case reports were identified. Using a random sampling method, we selected 12 case reports of TSC without rupture (control). We included our patient with TSC with rupture as the 12th case of TSC cohort with CR (CR group). Demographic and clinical characteristics were compared between CR group and control. Results: All patients in the TSC group with rupture were female and were significantly older than controls. TSC group with rupture had significantly higher frequency of ST elevation in lead II and absence of T-wave inversion in lead V5 on hospital admission than controls. Mean ejection fraction, systolic blood pressure, and double product, a measure of oxygen demand, was significantly higher in the rupture group compared to controls. The CR group was associated with less frequent use of β-blocker as compared to controls. Conclusions: CR as a complication of TSC could be more common than recognized. Higher double product and ejection fraction suggest higher fluctuation of intracardiac pressure and may cause CR in TSC. Use of β blockers in TSC may provide protection against CR. Methods Ovid MEDLINE (1950-2009) was searched for case reports with search terms ''Takotsubo cardiomyopathy,'' ''Takotsubo syndrome,'' ''stress cardiomyopathy,'' ''ampullary cardiomyopathy,'' and ''broken heart syndrome.'' A total of 375 case reports were identified with ''human'' and ''English'' as limits. Eleven case reports of TSC were identified with CR. All case reports were published during the years 2004 to 2009. To obtain a control group for comparison we searched MEDLINE for case reports with the same search terms spanning 2004 to 2009. We chose a random sampling method using a random number generator to select case reports. If the article matching the random number was not a case

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“…High intra-ventricular pressure was previously found in a patient with aortic stenosis, AMI and LVR, despite immediate reperfusion therapy [6]. Another condition often presenting with intra-ventricular gradient [7], which was reported as occasionally leading to LVR, is Tako-Tsubo cardiomyopathy [8,9]. Possibly, same phenomena linked to presence of intra-ventricular gradient may precipitate LV wall shear stress, leading to LV tear formation and LVR.…”

Section: Discussionmentioning

confidence: 93%