As demand for digital services grows, there is need to improve efficiency and reduce the environmental impact of data centers. The largest energy consumer in any data center is the IT, followed by the systems dedicated to cooling. Aiming to improve efficiency, and driven by metrics like PUE, there is a trend towards running data centers hotter to reduce the cooling energy. There is little research investigating the effect this will have on the IT beyond failure rates. To ensure overall efficiency is improving, we must view the data center as a system of systems, taking a holistic view rather than focusing on individual sub-systems. In this paper we use industry standard benchmarks and a wind-tunnel to profile typical enterprise IT. We analyze the effect of environmental conditions on IT efficiency, showing minor increases in temperature or pressure impact the efficiency of servers. Using an idealized, simulated data center case study we show that the interaction between cooling systems, server behavior and local climate are non-trivial and increasing temperatures has potential to worsen efficiency.