A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale

Mohammad, Faryal Vali; Noorwala, Mushtaq; Ahmad, Viqar Uddin; Şener, Bilge

doi:10.1016/0031-9422(95)00246-4

Cited by 20 publications

(10 citation statements)

References 22 publications

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“…The glycosidic linkages of the sugars were established by the GC-MS analysis of methylated methyl monosaccharides. These results were consistent with the 13C-NMR data of the saponins (see Table 2) (6)(7)(8)(9)(10)(11)(12).…”

Section: I8m (H-3a)supporting

confidence: 90%

“…TheIR spectrum oftranssylvanosideJ 2 The negative ion FAB-MS of 2 showed a quasimolecular ion peak at m/z = 1235 EM -H]-, (consistent with the molecular formula C59}-196027), followed by the fragments at m/z = 1073, 911, 749, 603, and 471. The base peak of the spectrum at m/z = 911 suggested that a glucose-glucose chain was linked to hederagenin by an ester function (12). Alkaline hydrolysis of 2 supported this result by giving a new prosapogenin (5).…”

Section: I8m (H-3a)mentioning

confidence: 88%

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Hederagenin Glycosides from the Flowers ofCephalaria transsylvanica

Kirmizigul

Rose²

1997

Planta Med

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Three new triterpenoidal saponins, 3-O-[beta-D-glucopyranosyl(1-->4)-beta-D-Glucopyranosyl(1-->3)-alpha-L- rhamnopyranosyl (1-->4)-beta-D-xylopyranosyl]-hederagenin 28-O-[beta-D-glucopyranosyl (1-->4)-beta-D-glucopyranosyl] ester (1), 3-O-[beta-D-glucopyranosyl (1-->3)-alpha-L-rhamnopyranosyl(1-->2)-beta-D-xylopyranosyl]-hederage nin 28-O-[beta-D-glucopyranosyl(1-->4)-beta-D-glucopyranosyl] ester (2), and 3-O-[alpha-L-rhamnopyranosyl(1-->4)-beta-D-xylopyranosyl]-hederagenin (3) were isolated from the flowers of Cephalaria transsylvanica. Two new prosapogenins, 3-O-[beta-D-glucopyranosyl (1-->4)-beta-D-glucopyranosyl(1-->3)-alpha-L-rhamnopyranosyl(1-->4)- beta-D-xylopyranosyl]-hederagenin (4) and 3-O-[beta-D-glucopyranosyl (1-->3)-alpha-L-rhamnopyranosyl(1-->2)-beta-D-xylopyranosyl]-hederage nin (5) were also isolated after cleavage of the ester-glycosidic linkage of the bisdesmosidic compounds. Structure elucidation was carried out chemically and spectroscopically.

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Section: I8m (H-3a)supporting

confidence: 90%

Section: I8m (H-3a)mentioning

confidence: 88%

Hederagenin Glycosides from the Flowers ofCephalaria transsylvanica

Kirmizigul

Rose²

1997

Planta Med

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“…Com relação ao confrey, possui na sua composição alcalóides pirrolizidínicos, alantoína, tanino (ROSLINDO et al, 1999) e saponinas triterpenóides (MOHAMMAD et al, 1995).…”

Section: Introductionunclassified

Comparação Entre Fitoterápicos De Uso Tópico Na Cicatrização De Pele Em Eqüinos

Martins¹,

Alves²,

Hussni³

et al. 2003

AVS

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Foram utilizados seis eqüinos adultos sem raça definida (SRD), com o objetivo de estudar os aspectos macroscópicos e histopatológicos da cicatrização de pele por segunda intenção, em feridas provocadas cirurgicamente e tratadas topicamente por fitoterápicos: barbatimão (Stryphnodendron barbatiman), calêndula (Calendula officinalis) e confrey (Symphytum officinale), tendo a solução salina como controle das demais. Foram feitas quatro lesões de cada lado da região lombar, do lado direito destinadas à macroscopia e do lado esquerdo à análise histopatológica. As lesões foram tratadas diariamente, observando-se a evolução de cada ferida quanto à retração centrípeta e aspecto macroscópico, até a cicatrização completa. Finalizado o experimento, a análise estatística não revelou variações significativas no estudo comparativo dos fitoterápicos. As observações macroscópicas, histopatológica e a retração centrípeta do halo da lesão nos 15 primeiros dias permitiram concluir que o barbatimão revelou efeito benéfico no processo de cicatrização, seguido pela calêndula, sendo os resultados do grupo controle superiores ao confrey. Comparison between phytotherapics on equine wound healing Abstract It has been carried out a study on the macroscopic and histopathologic aspects of equine skin healing by second intention in wounds cirurgically performed and topically treated with phytotherapics: barbatiman (Stryphnodendrom barbattiman), calendula (Calendula officinalis) and confrey (Symphytum officinale) and physiological solution as control. Four lesions were performed in each side of the lumbar area: the ones in the right side for macroscopic observations and the ones on the left side for histopathologic analysis. The lesions were daily treated with the above mentioned phytotherapics. Each wounds was observed in regard to its centripetal contraction and macroscopic aspects until the complete healing. In this model, the statistic analysis did not reveal significant variations in regard to the comparative effect of the phytoterapics. Macroscopic observations, histopathologic analysis and wound area centripetal retraction in the first fifteen days displayed a beneficial effect of barbatiman in the healing process, better than the other treatment groups, followed by calendula. The results displayed by the control group showed to be superior when compared with confrey.

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“…Although various studies have been performed on Symphytum genus in recent years, most of them are pointed to their chemical structure, karyology and phylogenetic analysis including morphological and molecular characters (Ulubelen and Doğanca, 1971;Ahmad et al, 1993;Mohammed et al, 1995;Akçin and Baki, 2009;Cohen, 2013). The best of our knowledge, there is little available information on the embryologic characters of Symphytum.…”

Section: Introductionmentioning

confidence: 99%

Development of Male and Female Gametophyte in Symphytum orientale L. (Boraginaceae)

Vardar

Yavuz

2018

Not Sci Biol

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The presented study elucidates developmental features of male and female gametophyte in Symphytum orientale L. (Boraginaceae). Flower buds were collected from natural habitats (İstanbul-Turkey) in March-April. The anthers of S. orientale were tetrasporangiate with a persistent epidermis and its wall development conformed to the Dicotyledonous type. The endothecium developed fibrous wall thickenings. The middle layer was short-lived and the cells of the glandular tapetum became double nucleated. In the microspore mother cells cytokinesis originated simultaneously after meiosis and the microspore tetrads were tetrahedral or isobilateral. The mature pollen grains were 3-celled when spread to environment. The ovule was hemianatropous, unitegmic and tenuinucellar. The megaspore mother cell functioned directly from the archesporial cell. Polygonum type embryo sac developed from the chalazal megaspore of a linear tetrad generated after meiosis. The synergids were pyriform and the polar nuclei fused shortly before fertilization. The antipodal cells were large and persistent at the stage of globular embryo. Embryogenesis followed the Chenopodiad type and the endosperm represented cellular type. The detailed embryological data of Symphytum orientale L. (Boraginaceae), which is a herbaceous and perennial flowering plant will improve our knowledge of its reproductive behaviour, and provide to comprehend taxonomic connection with related taxa within the Symphytum/Boraginaceae.

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A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale

Cited by 20 publications

References 22 publications

Hederagenin Glycosides from the Flowers ofCephalaria transsylvanica

Hederagenin Glycosides from the Flowers ofCephalaria transsylvanica

Comparação Entre Fitoterápicos De Uso Tópico Na Cicatrização De Pele Em Eqüinos

Development of Male and Female Gametophyte in Symphytum orientale L. (Boraginaceae)

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