A Biermer’s Disease Revealed by a Myogeneous Syndrome About a Rare Case in Young African Black Subject and Literature Review

Abstract

Biermer's disease is an autoimmune disorder characterized by vitamin B12 deficiency. Neurological symptoms of B12 vitamin deficiency are polymorph. We report a case of a young black girl of 28 years old, senegalese student, consulted for walking ataxia and myalgia. The neurological examination found a myogenic syndrome of the four limbs. The electroneuromyogram showed diffuse myogenic involvement. The biological assessment found a macrocytic anemia at 112 fL with a vitamin B12 level collapsed at 74 pmol/L. The anti-parietal cell and anti-intrinsic factor were positive. Under supplementation with vitamin B12 the evolution is favorable after 8 months of treatment. Thus neurological deficiencies due to vitamin B12 deficiency are polymorphic. The dosage of vitamin B12 must be done before any neuropsychiatric symptoms that does not prove its worth.