A bioactive titanium foam scaffold for bone repair

Spoerke, Erik David; Murray, N. G.D.; Li, Huanlong; Brinson, L. Catherine; Dunand, David C.; Stupp, Samuel I.

doi:10.1016/j.actbio.2005.04.005

Cited by 183 publications

(120 citation statements)

References 50 publications

Supporting

Mentioning

114

Contrasting

Unclassified

Order By: Relevance

“…The bubbles can be created by gas by-products of the chemical reaction or injected externally. Ceramic foams [12], polymeric foams [13] and metal foams [14] have been manufactured via this method which does not provide a high control on the porosity gradation per se. If engineered foams are intended, a better control on the gas injection, or production, is needed.…”

Section: Controlled 'Bubble Forming' Techniquesmentioning

confidence: 99%

Morphological and biological characterization of density engineered foams fabricated by ultrasonic sonication

Torres-Sánchez

Corney

2010

J Mater Sci

View full text Add to dashboard Cite

show abstract

Section: Controlled 'Bubble Forming' Techniquesmentioning

confidence: 99%

Morphological and biological characterization of density engineered foams fabricated by ultrasonic sonication

Torres-Sánchez

Corney

2010

J Mater Sci

View full text Add to dashboard Cite

show abstract

“…considers porous materials and adjusts porosity to match the elastic modulus of human bone [21,22]; the second relates to the utilization of HAP [23,24]; the third focuses on bulk materials that present low intrinsic elastic constants. The third approach was first introduced in Japan at the beginning of the 2000s [25].…”

mentioning

confidence: 99%

Interaction of bone–dental implant with new ultra low modulus alloy using a numerical approach

Piotrowski

Baptista²,

Patoor

et al. 2014

Materials Science and Engineering: C

View full text Add to dashboard Cite

Although mechanical stress is known as being a significant factor in bone remodeling, most implants are still made using materials that have a higher elastic stiffness than that of bones.Load transfer between the implant and the surrounding bones is much detrimental, and osteoporosis is often a consequence of such mechanical mismatch. The concept of mechanical biocompatibility has now been considered for more than a decade. However, it is limited by the choice of materials, mainly Ti-based alloys whose elastic properties are still too far from cortical bone. We have suggested using a bulk material in relation with the development of a new beta titanium-based alloy. Titanium is a much suitable biocompatible metal, and betatitanium alloys such as metastable TiNb exhibit a very low apparent elastic modulus related to the presence of an orthorhombic martensite. The purpose of the present work has been to investigate the interaction that occurs between the dental implants and the cortical bone. 3D finite element models have been adopted to analyze the behaviour of the bone-implant system depending on the elastic properties of the implant, different types of implant geometry, friction force, and loading condition. The geometry of the bone has been adopted from a mandibular incisor and the surrounding bone. Occlusal static forces have been applied to the implants, and their effects on the bone-metal implant interface region have been assessed and 2 compared with a cortical bone/ bone implant configuration. This work has shown that the low modulus implant induces a stress distribution closer to the actual physiological phenomenon, together with a better stress jump along the bone implant interface, regardless of the implant design.Keywords: Dental biomechanics, Beta titanium alloy, Low modulus implant, Numerical modelling, Bone-implant interface IntroductionOver the last few decades, considerable progress in dental implantology has been made, with success rates exceeding 95% [1]. Implant stability is commonly considered as playing a major role in a successful osseointegration. Obtaining post-operative osseointegration is necessary in order to establish a solid and durable connection between the implant and the osseous structure. In agreement with the Wolff law, a process of osseous remodelling adapted to the stress level occurs after implantation [2][3][4]. This process is controlled by mechanical loads.When the occlusal forces induced on the bone exceed a physiological level, bone resorption can occur, with possible failure [5]. More importantly, the long-term performance of an implant is known to be strongly dependent on the bone tissue interaction [6]. The strain state which takes place at the interface between the bone and implant controls the bone tissue remodelling mechanisms [7]. Bone resorption is associated with a low strain state, and bone necrosis occurs when strain exceeds the maximum level.Evaluation of the risk requires a comprehension of the load transfer along the bone-dental implant interface. T...

show abstract

“…In the recent years, porous titanium and titanium alloys are used extensively as biomedical materials for dental implants, hip and knee joints [6][7][8]. By controlling porosity content, mechanical properties of porous materials can be adjusted.…”

Section: Introductionmentioning

confidence: 99%

Comparison of the Mechanical Response of Porous Ti-6al-4v Alloys Produced by Different Compaction Techniques

Selimoğlu¹,

Aşık²,

Şen³

et al. 2017

ANADOLU UNIVERSITY JOURNAL OF SCIENCE AND TECHNOLOGY a - Applied Sciences and Engineering

View full text Add to dashboard Cite

Porous Ti-6Al-4V alloys are attractive candidates as implant materials due to their good biocompatibility combined with the porous structure leading to increased osseointegration and decreased stiffness. Accordingly, different processing techniques were employed for the production of Ti-6Al-4V foams in the literature. Among these techniques, sintering with space holder is used to produce porous Ti-6Al-4V alloys in this study. Magnesium was employed as the space holder material because of its relatively low boiling point as well as high oxygen affinity. Two different compaction techniques, die compaction with hydraulic pressing and cold isostatic pressing (CIP), were employed for obtaining green compacts. Both spherical and nonspherical Ti-6Al-4V powders were used to investigate the effect of powder shape on compaction. Processed foams were characterized in terms of both microstructural and mechanical aspects in order to investigate the effect of pressing conditions in combination with powder characteristics. It was observed that NS-CIP foam, which was produced by compacting nonspherical powders by cold isostatic press, has the highest strength. However, the S-DP foam, which was produced by diepressing of spherical powders, has the highest toughness.

show abstract

A bioactive titanium foam scaffold for bone repair

Cited by 183 publications

References 50 publications

Morphological and biological characterization of density engineered foams fabricated by ultrasonic sonication

Morphological and biological characterization of density engineered foams fabricated by ultrasonic sonication

Interaction of bone–dental implant with new ultra low modulus alloy using a numerical approach

Comparison of the Mechanical Response of Porous Ti-6al-4v Alloys Produced by Different Compaction Techniques

Contact Info

Product

Resources

About