1970
DOI: 10.1146/annurev.bi.39.070170.000245
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A Biochemist's Anabasis

Abstract: Annu. Rev. Biochem. 1970.39:1-25

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Cited by 12 publications
(2 citation statements)
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“…These two constants, K¢, the association constant for C02, and Kz, the dissociation constant for the proton of the amine define the affinity of that amine for CO2 and protons, respectively (Eqs. 1 and 2). Carbamino formation is favored if both pK, and pK, are low.…”
Section: Pk Determinationmentioning
confidence: 96%
See 1 more Smart Citation
“…These two constants, K¢, the association constant for C02, and Kz, the dissociation constant for the proton of the amine define the affinity of that amine for CO2 and protons, respectively (Eqs. 1 and 2). Carbamino formation is favored if both pK, and pK, are low.…”
Section: Pk Determinationmentioning
confidence: 96%
“…Carbon dioxide produced by various metabolic reactions within cells is hydrated to carbonic acid and subsequently ionized to hydrogen and bicarbonate ions, providing the components of the major extracellular buffering system. Although levels of both hydrogen ions and carbon dioxide are carefully controlled, circulating levels of carbon dioxide are more carefully controlled than those of hydrogen ion (1). Separate effects of each for regulatory processes have been sought (2), whereas less attention has been given to their combined effects on metabolic pathways or processes through carbamino formation with molecules other than hemoglobin.…”
Section: Introductionmentioning
confidence: 99%