A Biomineralized Bifunctional Patient‐Friendly Nanosystem for Sustained Glucose Monitoring and Control in Diabetes
Zhe Yang,
Yuen‐Man Chan,
Daniel Shiu‐Hin Chan
et al.
Abstract:Regular blood glucose monitoring and control is necessary for people with type 1 or advanced type 2 diabetes, yet diagnosing and treating patients with diabetes in an accurate, sustained and patient‐friendly manner remains limited. Here, a glucose‐responsive bifunctional nanosystem (PGOxMns) is constructed via one‐pot biomineralisation of manganese dioxide with glucose oxidase and ε‐poly‐L‐lysine. Under hyperglycaemic conditions, the cascade reactions that occur when glucose interacts with PGOxMns can trigger … Show more
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