A Blood Flowmeter for Use in Coronary Heart Disease Research

Giori, F. A.

doi:10.1109/iret-me.1960.5008050

Cited by 3 publications

(1 citation statement)

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“…Methods employed to study gastric emptying (aspiration, X-ray and ycamera methods) provide information about the percentage or fraction of the meal remaining in the stomach at various times after ingestion (Elashoff, Reedy & Meyer, 1982). In order to quantify the rate of passage of digesta through this region and define the patterns of flow both near the pylorus and 4-5 cm aborally, it is appropriate to use flowmeter probes like those used to record blood flow through intact vessels (Giori, 1960). In sheep, the temporary presence of a flowmeter probe does not impair motility or the pattern of flow and the relations between antroduodenal contractile activity and the resulting movements of digesta have recently been established in this way (Malbert & Ruckebusch, 1988).…”

Section: Introductionmentioning

confidence: 99%

Duodenal bulb control of the flow rate of digesta in the fasted and fed dog.

Malbert

Ruckebusch

1989

The Journal of Physiology

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SUMMARY1. Continuous measurement of the flow of digesta near the pylorus, and 5 cm aborally, was assessed in the conscious dog using a chronically implanted flowmeter. The patterns of flow were related to motor activity of the gastroduodenal junction.2. Electromagnetic measurement of the flow was calibrated in vitro by means of a pulsatile pump. Validation was obtained in vivo by direct evaluation of the amount of chyme collected from an open duodenal cannula and indirectly by a dye-dilution technique.3. After a 12 h fast, only small amounts of gastric contents were delivered into the duodenum. This transfer occurred during periods of irregular motor activity recorded along the gastroduodenal junction, which occupied less than 25% of the recording time. The patterns of flow near the pylorus and beyond the duodenal bulb were correlated to antral and duodenal contractions respectively. 4. After a meal, gastric emptying occurred intermittently and was related to enhanced antral motor activity beyond the duodenal bulb; digesta flowed in clusters of gushes which were related to the duodenal contractions.5. It is concluded that the mechanical role of the duodenal bulb is to change the intermittent juxtapyloric flow of digesta into a uniform flow at the duodenal level.

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Section: Introductionmentioning

confidence: 99%