A BODIPY derivative as a colorimetric, near-infrared and turn-on chemosensor for Cu2+

Revisiting the optical signatures of BODIPY with ab initio tools

“…BODIPY and its derivatives have been widely used as ion sensors, 33,76,125,150,151,[157][158][159][160][161][162][163][164][165] and a selected set of representative molecules can be found in Fig. 14.…”

Polypyridyl substituted BODIPY derivatives; water switchable imaging probes that exhibit halogen substituent dependent localisation in live cells

“…Finally, BODIPY derivatives with appended coordination sites have been widely studied as sensors for transduction of metal ion binding reported through uorescence. [5][6][7]11,12,19,24,25,[31][32][33][34][35][37][38][39][40][41][42][43][44][45][46] We have also recently shown that complexation of a ruthenium metal centre to a polypyridylbased BODIPY uorophore does not alter BODIPY emission permitting the use of the complex as a ratiometric oxygen sensor. 35 As the reported BODIPY derivatives are functionalised at the meso-position with metal coordinating ligands, we report a preliminary investigation into their ability to complex biologically relevant metal ions in non-aqueous media and the effect of metal binding on photophysical properties of the dyes.…”

Ratiometric fluorescence sensing and cellular imaging of Cu2+ by a new water soluble trehalose-naphthalimide based chemosensor

“…16 Most of the reported copper(II) uorescent chemosensors are based on the quenching effect caused by the paramagnetic nature of Cu 2+ and, thus, belong to the turn-off class. [17][18][19][20] Fluoroionophores showing a turn-on response (uorescence enhancement) as a result of the metal-ion interaction are obviously more attractive as proved by their rapidly increasing number. [21][22][23] However, only few chemosensors from this class have good solubility in water, which is a key issue for applications in biological systems.…”