2012
DOI: 10.1017/s0021900200009621
|View full text |Cite
|
Sign up to set email alerts
|

A Branching Process for Virus Survival

Abstract: Abstract. Quasispecies theory predicts that there is a critical mutation probability above which a viral population will go extinct. Above this threshold the virus loses the ability to replicate the best adapted genotype, leading to a population composed of low replicating mutants that is eventually doomed. We propose a new branching model that shows that this is not necessarily so. That is, a population composed of ever changing mutants may survive.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2016
2016
2016
2016

Publication Types

Select...
2

Relationship

1
1

Authors

Journals

citations
Cited by 2 publications
(2 citation statements)
references
References 8 publications
0
2
0
Order By: Relevance
“…The model with locally changing environment is a discrete time generalization of a model introduced by Cox and Schinazi (2012). The results in this paper show that the phenomena observed in Cox and Schinazi (2012) for specific offspring distributions are in fact quite general.…”
Section: Locally Changing Environmentmentioning
confidence: 72%
“…The model with locally changing environment is a discrete time generalization of a model introduced by Cox and Schinazi (2012). The results in this paper show that the phenomena observed in Cox and Schinazi (2012) for specific offspring distributions are in fact quite general.…”
Section: Locally Changing Environmentmentioning
confidence: 72%
“…which can be derived by conditioning on Y t (see e.g. Section 2 of [CS12] or proof of Lemma 1 in Section 4 of [BL09]). Let D t be the number of deaths up to time t. Then we have the analogue differential equation…”
Section: Remarkmentioning
confidence: 99%