A brief campaign to prevent diabetic ketoacidosis in children newly diagnosed with type 1 diabetes mellitus: The NO-DKA Study

Abstract

A non-targeted campaign to raise awareness of diabetes symptoms in youth led only a few caregivers to seek timely medical attention. Overall, this once-yearly untargeted campaign to raise awareness of diabetes symptoms in youth had limited impact. More effective strategies are required, possibly involving sustained targeted education of medical practitioners.

Diabetic ketoacidosis in children newly diagnosed with type 1 diabetes mellitus: Role of demographic, clinical, and biochemical features along with genetic and immunological markers as risk factors. A 20‐year experience in a tertiary Belgian center

“…More recently, similar results were obtained by an information campaign in France . Nevertheless, a very recent once‐yearly untargeted campaign to raise awareness of diabetes symptoms in youth had limited impact . The efficiency and cost effectiveness of strategies to reduce the incidence of DKA at T1D onset are important issues for future interventions.…”

Temporal trends in diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes between 2006 and 2016: results from 13 countries in three continents

“…Our study did not collect information on local awareness campaigns but showed an increasing trend in the prevalence of DKA at diagnosis of type 1 diabetes over the 11 year period, suggesting that if prevention campaigns had been carried out locally, the expected effect was not achieved. Effective prevention campaigns should be targeted to reach a high percentage of the general population and healthcare professionals, should be repeated and prolonged over time, and should monitor all factors influencing the occurrence of DKA [ 15 ]. Preschool screening for islet autoantibodies in the general population might be useful to prevent DKA at diagnosis, as shown in a public health screening programme among children aged 2–5 years in Bavaria, Germany, in which the prevalence of DKA at diagnosis was less than 5% [ 43 ].…”

“…However, a cost-benefit analysis of a screening programme in the general population showed that costs far outweighed the economic benefits [13]. The impact of individual knowledge and community-based information and education campaigns in reducing DKA at type 1 diabetes onset has been disappointing [14][15][16]. These studies have suggested that knowledge of the symptoms of diabetes does not necessarily appear to translate to an earlier diagnosis.…”

Increased frequency of severe diabetic ketoacidosis at type 1 diabetes onset among children during COVID-19 pandemic lockdown: an observational cohort study

“…Literature suggests that increased awareness of T1D results in earlier diagnosis and treatment, can lead to DKA rate decrease [8,[33][34][35]. However, awareness publicity campaigns directed to type 1 diabetes have not shown consistent results [24,33,34,[36][37][38][39].…”