“…Vasa vasorum in veins also lie within the adventitia and penetrate the media in close proximity to the lumen ( 134 ). The presence and integrity of the vasa vasorum are thought to be important for vein graft patency ( 135 , 136 ). Saphenous vein graft harvest via a “no-touch” technique presumably protects the adventitia, preserves vasa vasorum endothelial function, and is considered to be superior to the conventional technique, which is less invasive and therefore imposes reduced donor site morbidity, but is more damaging to the harvested vessel itself in that it strips away the adventitia, thus removing most of the vasa vasorum ( 134 ).…”