“…Papers that were published between 1951 and 1955 regarding the first interventions for heart valve diseases recommended the use of very light anaesthesia to reduce cardiac depression that would occur at the induction of anaesthesia. Some authors reported beneficial effects provided by the associations between different anaesthetic drugs, while others adopted extreme measures to decrease the haemodynamic effects of anaesthesia, such as providing a mild sedation that left the patients almost awake during the operation [1,[6][7][8][9].…”