A Brief History of Organ and Tissue Transplantation in Azerbaijan

Bayramov, Nuru Yusifoglu; Gahramanova, Farah Afilqızı

doi:10.6002/ect.2021.0216

Cited by 2 publications

(1 citation statement)

References 1 publication

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“…A chronological flow of the significant landmarks [18][19][20] in kidney transplantation is shown in Figure 1. Tissue transplantation is now attempted in almost all human body organs; this scientific venture has explored the bones, the eyes, the skin, and solid organs [12,21]. A most recent account of how transplantation has evolved, especially genetic engineering, has been reported [22].…”

Section: Brief History Of Tissue Transplantationmentioning

confidence: 99%

Classic and Current Opinions in Human Organ and Tissue Transplantation

Oli¹,

Rowaiye²,

Adejumo³

et al. 2022

Cureus

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Graft tolerance is a pathophysiological condition heavily reliant on the dynamic interaction of the innate and adaptive immune systems. Genetic polymorphism determines immune responses to tissue/organ transplantation, and intricate humoral and cell-mediated mechanisms control these responses. In transplantation, the clinician's goal is to achieve a delicate equilibrium between the allogeneic immune response, undesired effects of the immunosuppressive drugs, and the existing morbidities that are potentially life-threatening. Transplant immunopathology involves sensitization, effector, and apoptosis phases which recruit and engages immunological cells like natural killer cells, lymphocytes, neutrophils, and monocytes. Similarly, these cells are involved in the transfer of normal or genetically engineered T cells. Advances in tissue transplantation would involve a profound knowledge of the molecular mechanisms that underpin the respective immunopathology involved and the design of precision medicines that are safe and effective.

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Section: Brief History Of Tissue Transplantationmentioning

confidence: 99%

Classic and Current Opinions in Human Organ and Tissue Transplantation

Oli¹,

Rowaiye²,

Adejumo³

et al. 2022

Cureus

View full text Add to dashboard Cite

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The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries

Duong,

Thai,

Tran

et al. 2024

SIUJ

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Kidney transplantation (KT) is a preferred treatment for end-stage renal disease (ESRD) because it offers better long-term survival and cost-effectiveness compared to dialysis. Significant global disparities persist in access to KT, particularly in low- and middle-income countries (LMICs). This study aims to assess the epidemiology and outcomes of KT in LMICs while examining the relationship between a country’s income level and its KT prevalence. A systematic review of the literature was conducted, with searches of PubMed, Scopus, and Web of Science from inception to 31 May 2024. Relevant articles reporting on the epidemiology and outcomes of KT or ESRD patients undergoing kidney replacement therapy (KRT) in LMICs were included. A total of 8054 articles were identified, with 972 articles selected for full-text screening after initial title and abstract review. Following full-text screening, 35 articles met the inclusion criteria. The data showed significant variation in KRT and KT prevalence across different geographical locations. Higher-income countries within LMICs tended to have higher KT prevalence rates. Barriers such as inadequate healthcare infrastructure, limited financial resources, and insufficient organ donation frameworks were identified as contributing factors to the low KT rates in these regions. The study highlights the disparities in KT access and prevalence in LMICs, underscoring the need for targeted interventions and international collaboration to address these gaps. Efforts to increase both living and deceased donor transplants, expand health system capacity, and incorporate KT in healthcare planning are needed to close this gap. Global partnerships spearheaded by organizations such as The Transplantation Society (TTS) and the International Society of Nephrology (ISN) are crucial for improving KT rates and outcomes in LMICs.

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A Brief History of Organ and Tissue Transplantation in Azerbaijan

Cited by 2 publications

References 1 publication

Classic and Current Opinions in Human Organ and Tissue Transplantation

Classic and Current Opinions in Human Organ and Tissue Transplantation

The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries

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