| With the advent of 5G technology, the notion of latency got a prominent role in wireless connectivity, serving as a proxy term for addressing the requirements for realtime communication. As wireless systems evolve toward 6G, the ambition to immerse the digital into physical reality will increase. Besides making the real-time requirements more stringent, this immersion will bring the notions of time, simultaneity, presence, and causality to a new level of complexity.A growing body of research points out that latency is insufficient to parameterize all real-time requirements. Notably, one such requirement that received significant attention is information freshness, defined through the Age of Information (AoI) and its derivatives. In general, the metrics derived from a conventional black-box approach to communication network design are not representative of new distributed paradigms, such as sensing, learning, or distributed consensus. The objective of this article is to investigate the general notion of timing in wireless communication systems and networks, and