A Canine Case of Mixed Carcinoma of the Sweat Gland in the Footpad

Abstract

A 9-year-old, castrated male mongrel dog had a mass in the footpad of the left hindlimb. Histologically, the tumor was composed of irregular tubuloacinar structures with desmoplasia, and apocrine secretion was

A Mixed Apocrine Gland Tumor with Metastases to the Bone and Bone Marrow in a Miniature Poodle

“…On the other hand, in apocrine gland tumors of the dog, there are few reports on such a tumor, but a report of mixed carcinoma of the sweat gland in the foot pad of a dog has previous been published. 9 In that report, it was difficult to make a differential diagnosis in regard to whether that tumor was derived from the apocrine or eccrine gland in the foot pad because there was no clear direct evidence that it should be diagnosed as a mixed apocrine gland tumor. 9 In the present tumor, the findings suggest that the tumor was composed of both epithelial components of the apocrine gland and stromal components of myoepithelial cells and chondroid/osteoid tissues, that it was not derived from the foot pad and that it should be diagnosed as “a mixed apocrine gland tumor”.…”

“… 9 In that report, it was difficult to make a differential diagnosis in regard to whether that tumor was derived from the apocrine or eccrine gland in the foot pad because there was no clear direct evidence that it should be diagnosed as a mixed apocrine gland tumor. 9 In the present tumor, the findings suggest that the tumor was composed of both epithelial components of the apocrine gland and stromal components of myoepithelial cells and chondroid/osteoid tissues, that it was not derived from the foot pad and that it should be diagnosed as “a mixed apocrine gland tumor”. Furthermore, the tumor cells invaded in the bone and bone marrow, which is a rare finding in dogs, and there is no description of this in the literature, as far as we know.…”

“…In animals, there is one report of osteoid formations accompanied by an apocrine gland tumor in a cow, and this tumor was diagnosed as “a malignant mixed apocrine gland tumor” 8 . On the other hand, in apocrine gland tumors of the dog, there are few reports on such a tumor, but a report of mixed carcinoma of the sweat gland in the foot pad of a dog has previous been published 9 . In that report, it was difficult to make a differential diagnosis in regard to whether that tumor was derived from the apocrine or eccrine gland in the foot pad because there was no clear direct evidence that it should be diagnosed as a mixed apocrine gland tumor 9 …”