A Carrel patch technique for renal transplantation in cats

Budgeon, Casey; Hardie, Robert J.; McAnulty, Jonathan F.

doi:10.1111/vsu.12705

Cited by 4 publications

(2 citation statements)

References 23 publications

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“…This modification allowed us to maximize the length of vessels and avoid damage to the graft artery. Budgeon et al reported that a carrel patch technique could reduce the risk of thrombosis and leakage by displacing the suture line away from the entrance to the renal artery (19). Carrel et al and Mazzucchi et al.…”

Section: Discussionmentioning

confidence: 99%

Reproducible porcine model for kidney allotransplantation of low weight miniature pig

Zhang¹,

Zheng²,

Zhang³

et al. 2022

Transl Androl Urol

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Background: Multiple porcine models have been established to study the mechanisms regarding kidney transplantation. With the development of xenotransplantation, the demand for a low weight miniature pig model has been increasing. A reliable and reproducible surgical technique to establish these models, and to address possible obstacles, has not been sufficiently defined in detail. The goal of the present study was to develop and optimize a low weight miniature pig porcine kidney transplantation model, including a comprehensive surgical description. Methods: Eight male Bama miniature pigs (12-15 kg) were randomly chosen as kidney donors and, to facilitate investigation of the transplanted kidney, had undergone contralateral nephrectomy. The procured kidneys were perfused with iced saline then immediately cold stored in the University of Wisconsin preservation solution. The recipients were randomly allocated to left-to-right or right-to-right groups. Serum creatinine and urine volume were recorded post-transplantation, and the pigs underwent euthanasia at seven days post-transplantation. Results: All eight pigs showed functioning grafts, immediately producing urine post-transplantation. The serum creatinine level increased the following transplantation gradually and reached a peak on the day of euthanasia. One renal artery thrombosis and one ureterovesical entrance stenosis were observed in the rightto-right group. No complications were observed in the left-to-right group. Conclusions: We developed and optimized a reproducible porcine kidney transplantation model in the low weight miniature pig. Moreover, we addressed and emphasized critical points of the left-to-right transplantation surgery and detailed the anatomic techniques to avoid stenosis of blood vessels and prevent ureterovesical stricture.

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Section: Discussionmentioning

confidence: 99%

Reproducible porcine model for kidney allotransplantation of low weight miniature pig

Zhang¹,

Zheng²,

Zhang³

et al. 2022

Transl Androl Urol

View full text Add to dashboard Cite

show abstract

“…The graft's main renal artery is anastomosed to the recipient's external or internal iliac artery in end-to-side or end-toend anastomosis, respectively. With multiple donor renal arteries, an aortic patch ("Carrell patch"-containing the multiple renal arteries) is used to anastomose to the recipient's external iliac artery [13]. The main renal vein is anastomosed to the recipient's external or internal iliac vein.…”

Section: Introductionmentioning

confidence: 99%