“…Although the pathogenesis of catatonia remains unknown, it is hypothesized to involve immune dysregulation resulting in the neurovegetative symptoms of the disorder, including immobility and decreased oral intake. 16 , 17 , 18 Catatonia and related syndromes have been described in the setting of other infectious illnesses, including malaria, syphilis, human immunodeficiency virus, and prion diseases. 16 Of cases of catatonia with a general medical cause, infectious and immune causes accounted for 29% in 1 study, and a recent systematic review identified 124 infective cases of catatonia.…”