A Case-Based Approach to Constipation in Primary Care

Snell, David; Faruqui, Saamia; Bosworth, Brian

doi:10.1016/j.mcna.2020.08.015

Cited by 3 publications

(2 citation statements)

References 46 publications

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“…Although traditional teaching defines constipation as the number of stools per week, patients mainly complain about other symptoms, such as fatigue and stool consistency, rather than frequency. Symptoms need to be associated with possible causes, excluding secondary causes and treatment should be symptom-oriented to distinguish between functional constipation and irritable bowel syndrome complicated with constipation (Dzierzanowski & Mercadante, 2022; Snell et al, 2021). Pelvic floor dysfunction, which is more common in the elderly, should also be considered (Vazquez Roque & Bouras, 2015).…”

Section: Discussionmentioning

confidence: 99%

Influencing Factors of Constipation in Elderly Patients With Intracerebral Hemorrhage: Implication for Clinical Care

Wang,

Lu,

et al. 2024

Biological Research For Nursing

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Background: Constipation is common in elderly inpatients with intracerebral hemorrhage. This study aimed to construct a model for predicting the risk of constipation in elderly inpatients with intracerebral hemorrhage and to provide reference for formulating targeted intervention measures. Methods: Elderly patients with intracerebral hemorrhage who were treated in the department of Neurosurgery of a third-class hospital in Suzhou from January 2018 to September 2023 were included. Clinical data of patients with and without constipation were compared. Logistic regression analysis was used to explore the influencing factors of constipation in elderly patients with intracerebral hemorrhage, and R software was used to construct a line chart model to verify its predictive effect. Results: A total of 504 elderly patients with intracerebral hemorrhage were included. The incidence of constipation in elderly patients with cerebral hemorrhage was 63.9%. Logistic regression analysis showed that GCS score (OR = 1.094, 95%CI: 1.019∼1.174), hypertension (OR = 2.911, 95%CI: 1.797∼4.715), use of dehydrating agent (OR = 3.794, 95%CI: 2.337∼6.158), surgical treatment (OR = 3.986, 95%CI: 2.339∼6.793), use of sedative drugs (OR = 4.212, 95%CI:2.386-7.435), and limb paralysis (OR = 6.313, 95%CI:3.689∼10.803) were the independent risk factors for constipation in elderly patients with intracerebral hemorrhage. The area under the ROC curve of the prediction model was 0.872 (95%CI: 0.8401∼0.9033), the best critical value was 0.705, the sensitivity was 0.748, and the specificity was 0.857. Conclusion: The constipation risk prediction model of elderly patients with cerebral hemorrhage has good differentiation and calibration, which is helpful for health care providers to identify the risk of constipation in elderly patients with intracerebral hemorrhage.

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Section: Discussionmentioning

confidence: 99%

Influencing Factors of Constipation in Elderly Patients With Intracerebral Hemorrhage: Implication for Clinical Care

Wang,

Lu,

et al. 2024

Biological Research For Nursing

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“…This study may not reflect the whole society since only the group of employed people were included in the survey. Low socioeconomic status and low level of education are risk factors for constipation 24 . The nutritional habits and thus rates of constipation may not reflect the whole society since the participants in the survey had a definite level of income and level of education.…”

Section: Discussionmentioning

confidence: 99%

Constipation in the period of limited isolation during COVID-19 pandemic

Kayaoğlu

Sert

2022

Rev. Assoc. Med. Bras.

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OBJECTIVE: COVID-19 outbreak has become widespread globally and caused a new global chaos. This outbreak that completely affected the lifestyle of individuals resulted in periods of isolation. Here, we evaluated the effects of lifestyle changes with isolation on constipation. METHODS: A survey on constipation was performed during the 12-week isolation period starting in March 2020 in Turkey. Data of 390 individuals who participated in the survey through the social media and who were actively employed prior to isolation were analyzed. Rome IV criteria were used to evaluate constipation. RESULTS: Among the participants in the study, 253 (64.9%) were women with the mean age of 39.5±9.5 years. A statistically significant association was found between the decreased water consumption during the isolation period and constipation after the isolation (p=0.020; p<0.05). A significant association was found between the changes in physical activity and constipation after the isolation (p=0.013; p<0.05). New development of constipation during the isolation or declaration of increased constipation was found to be statistically associated with post-isolation constipation according to Rome criteria (p=0.000; p<0.05). CONCLUSION:The data of this present study demonstrated that isolation period was effective on the newly developed constipation. Decreased physical activity and water consumption are also effective on constipation.

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Safety of elobixibat and lubiprostone in Japanese patients with chronic constipation: a retrospective cohort study

Ooba

Takahashi

Nagamura

et al. 2021

Expert Opinion on Drug Safety

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Background: We aimed to discuss and compare reported adverse reactions and drug add-ons associated with elobixibat and lubiprostone use in chronic constipation treatment, as the safety of these drugs has not been well examined in post-marketing clinical settings. Research Design and Methods: In this retrospective cohort study, using records of community pharmacies in Japan, we identified new users of elobixibat and lubiprostone. The Japan Pharmaceutical Association sent questionnaires regarding baseline and event data to community pharmacists. The incidence of events and hazard ratio (HR) associated with the study drugs were evaluated. Results: New users of elobixibat (n = 979) and lubiprostone (n = 829) were identified (mean age: 74 and 77 years; females: 59% and 53%, respectively). Although the crude risk ratio of adverse events for elobixibat was 0.79 (95% confidence interval: 0.63-0.99), there was no significant difference in the HR for any of the common events, including drug add-ons (n ≥ 5), compared with those for lubiprostone. Conclusion:No new safety concerns have been raised in relation to elobixibat and lubiprostone use for treating chronic constipation, although the HR of different events varied. Further larger-scale study is needed as the estimates for events of small numbers were unstable ARTICLE HISTORY

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A Case-Based Approach to Constipation in Primary Care

Cited by 3 publications

References 46 publications

Influencing Factors of Constipation in Elderly Patients With Intracerebral Hemorrhage: Implication for Clinical Care

Influencing Factors of Constipation in Elderly Patients With Intracerebral Hemorrhage: Implication for Clinical Care

Constipation in the period of limited isolation during COVID-19 pandemic

Safety of elobixibat and lubiprostone in Japanese patients with chronic constipation: a retrospective cohort study

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