“…Compared with other imaging modalities, TOCU has the advantages of bedside availability, lesser invasiveness, lower cost, absence of exposure to radiation, and no significant contraindication. In recent case reports, intravenous injection of ultrasound contrast agents (either perfluorobutane: Sonazoid, Daiichi Sankyo, Tokyo, Japan, or sulfur hexafluoride: Sonovue, Bracco, Milan, Italy), produce a clear image of the distal extracranial ICA lumen which cannot be easily reached from the neck . Thus, TOCU and CE‐TOCU are additional approaches to conventional imaging modalities such as carotid ultrasonography, computerized X‐Ray tomography (CT), magnetic resonance imaging (MRI), and magnetic resonance angiography (MRA) for the evaluation of carotid artery dissection.…”