2015
DOI: 10.1099/jmmcr.0.000103
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A case of abscess after BCG vaccine in an immunocompetent child without other clinical signs

Abstract: Introduction: Bacille Calmette-Gué rin (BCG), an attenuated strain of Mycobacterium bovis, is a rare cause of infection, with few published cases in immunocompetent individuals. Case presentation: We present the case of a cutaneous abscess in an immunocompetent infant returning from Morocco, where he received a BCG vaccination. The abscess developed at the site of inoculation in the forearm (a non-recommended site) in the absence of lymphadenopathy or systemic signs. The lesion did not recur after aspiration o… Show more

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Cited by 4 publications
(2 citation statements)
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“…[ 8 ] d’Aleo F reported exaggerated response at the injection when BCG was administered into the subcutaneous space instead of intradermal inoculation which resulted in development of local abscess. [ 9 ] Looking in to the skills required for the intradermal injection and paramedical staff working with PPE kits on, we believe there are chances of erroneous injection of Mw in to the subcutaneous space, instead of intradermal space, in some of the patients. We are reporting this case to make clinicians aware that this can also occur as adverse site reaction which resolved with oral anti-inflammatory drugs and local steroids for 8 to 10 days.…”
Section: Discussionmentioning
confidence: 99%
“…[ 8 ] d’Aleo F reported exaggerated response at the injection when BCG was administered into the subcutaneous space instead of intradermal inoculation which resulted in development of local abscess. [ 9 ] Looking in to the skills required for the intradermal injection and paramedical staff working with PPE kits on, we believe there are chances of erroneous injection of Mw in to the subcutaneous space, instead of intradermal space, in some of the patients. We are reporting this case to make clinicians aware that this can also occur as adverse site reaction which resolved with oral anti-inflammatory drugs and local steroids for 8 to 10 days.…”
Section: Discussionmentioning
confidence: 99%
“…BCG and its cell wall component are highly immunogenic and may cause some cutaneous complications at the injection site [30,31]. Therefore, the safety of BCG-CWS was assessed as described in the Materials and Methods section.…”
Section: Determination Of the Reactogenicity Of Tested Vaccine Candidatementioning
confidence: 99%