A Case of Acute Disseminated Encephalomyelitis in a MIddle-Aged Adult

Mahdi, Nicole; Abdelmalik, Peter A.; Curtis, Mark; Bar, Barak

doi:10.29046/jhnj.011.1.001

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2016

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“…Within 5 years of initial presentation of ADEM, MS has been reported in ∼25% of patients. The majority of individuals do not progress beyond 3 months 16. Our patient showed a normal brain MRI after 6 months; also, her VEP study was normal after 6 months.…”

Section: Discussionmentioning

confidence: 49%

Acute disseminated encephalomyelitis in a case of autoimmune haemolytic anaemia: a rare association

Hajra

Bandyopadhyay²

2016

BMJ Case Reports

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Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease that may occur in a postvaccination condition or as a parainfectious encephalomyelitis. It is almost always monophasic. The underlying pathogenesis of ADEM may include perivascular inflammation, oedema and demyelination in the central nervous system. We present a case of a 15-year-old girl who was diagnosed as having ADEM, as well as detected to be a follow-up case of autoimmune haemolytic anaemia on steroid treatment. She presented with progressive weakness of the right lower limb for the past 4 days. MRI showed multiple subcortical lesions of varying size showing hyperintensities in T2 fluid-attenuated inversion recovery (FLAIR). The patient responded well to steroid therapy. No residual lesion was found on follow-up. Very few cases have been found with this rare association in the literature.

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Section: Discussionmentioning

confidence: 49%