A  case  of  adenoid  cystic  carcinoma  of  the  breast

Nozoe, Tetsuo; Nozoe, Emiko; Ohga, Takefumi; Ezaki, Takahiro; Sueishi, Katsuo

doi:10.2152/jmi.65.289

Cited by 4 publications

(1 citation statement)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mainstay of treatment of ACCB has not yet been established due to its rare incidence and indolent behavior, which can be confirmed in the literature, as there are mainly case reports, [7][8][9][10][11] or small series. 2,3,12,13 Regarding histological classification, several scores can be applied.…”

Section: Introductionmentioning

confidence: 99%

Adenoid Cystic Carcinoma of the Breast: An Oncological Center's Experience

et al. 2022

View full text Add to dashboard Cite

Background: Adenoid cystic carcinoma of the breast (ACCB) is a rare breast malignancy. Despite often being a triple negative tumor, it has a favorable prognosis, with low rates of recurrence and progression. The ideal treatment of ACCB is debatable; thus, the aim of this study was to characterize a population diagnosed with ACCB and to evaluate the treatment outcomes.Methods: We performed a single-center retrospective analysis of patients with a histological diagnosis of ACCB treated at our dedicated Oncological Center between 1987 and 2020. The patients were identified in collaboration with the Anatomical Pathology Department, which also reviewed the surgical pathology reports.Results: Thirteen women with a median age of 68 years old were diagnosed with ACCB. The most frequent clinical diagnosis was a breast nodule (n=5); the preoperative image was suggestive of malignancy in nine patients, with seven being diagnosed with a ACCB in the preoperative biopsy. Regarding treatment, nine patients underwent conservative surgery, but three required re-excision. Sentinel lymph node biopsy (SLNB) was performed in seven patients, none revealing metastases; one patient had stage III ACCB and was initially treated with a modified radical mastectomy (MRM); the remaining were stage I (n=7) and II (n=5). Adjuvant radiotherapy was performed in eight patients, and two were initially proposed for chemotherapy but were considered unfit. With a median follow-up of 123 months (16-407), one case of local recurrence and two cases of distant metastasis were identified, one of whom died of disease. Conclusion: ACCB is a rare tumor with a good prognosis; however, as demonstrated, it can present an aggressive behavior. Conservative surgery and adjuvant radiotherapy are the indicated treatment and SLNB may be omitted in grade 1 tumors.

show abstract

Section: Introductionmentioning

confidence: 99%

Adenoid Cystic Carcinoma of the Breast: An Oncological Center's Experience

et al. 2022

View full text Add to dashboard Cite

show abstract

Mammary adenoid cystic carcinoma presenting with Ductal carcinoma in situ and axillary lymph node metastasis

Burusapat

Buarabporn

Wongchansom

et al. 2020

Journal of Surgical Case Reports

View full text Add to dashboard Cite

Mammary adenoid cystic carcinoma (ACC) is extremely rare tumors, comprising <0.1% of all breast cancers. Moreover, lymph node metastasis is <2% of mammary ACC. Here, we report a case of 51-year-old female presented with painful mass on her left breast and left axillary lymph node enlargement. Core needle biopsy revealed invasive ductal carcinoma. Left lumpectomy and axillary lymph nodes dissections were performed. The final pathological report showed triple-negative mammary ACC arising with high grade ductal carcinoma in situ (DCIS) and axillary lymph node metastasis. Immunohistochemistry study is useful in confirming a diagnosis. Given the rarity of this cancer, natural history of disease is still not clearly understood. Complete surgical excision is the mainstay of treatment. To our best knowledge, mammary ACC presenting with DCIS and axillary lymph node metastasis has never been reported and should be considered in the differential diagnosis of breast cancers.

show abstract

Triple negative breast cancer: special histological types and emerging therapeutic methods

Cao

Niu

2020

Cancer Biol. Med.

View full text Add to dashboard Cite

A case of adenoid cystic carcinoma of the breast

Cited by 4 publications

References 16 publications

Adenoid Cystic Carcinoma of the Breast: An Oncological Center's Experience

Adenoid Cystic Carcinoma of the Breast: An Oncological Center's Experience

Mammary adenoid cystic carcinoma presenting with Ductal carcinoma in situ and axillary lymph node metastasis

Triple negative breast cancer: special histological types and emerging therapeutic methods

Contact Info

Product

Resources

About