A case of adult-onset asthma and periocular xanthogranuloma treated with systemic steroids

Abstract

Adult orbital xanthogranulomatous disease is a rare disorder which may or may not be associated with a systemic involvement. Herein, we report a 60-year-old male who presented with periocular swelling around the eyes for six years with history of asthma and rhinosinusitis. The diagnosis was confirmed by biopsy which showed multiple foci of lymphoid follicles, foamy histiocytes, and macrophages suggestive of the xanthogranulomatous lesion. The findings correlated with adult-onset asthma and periocular xanthogranuloma. He was treated with systemic steroids along with immunomodulator. We report this case owing to rarity of its occurrence, to discuss its management and to create awareness among ophthalmologists about this rare entity.