A case of Bacillus cereus bacteraemia

Barnham, M.; Taylor, A. J.

doi:10.1136/pgmj.53.621.397

Cited by 8 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pneumonia commonly occurs as a result of hematogenous dissemination of the organism (67,86,100,156,186,297). Table 1 summarizes the studies described and other case reports (12,13,54,65,67,68,86,98,100,111,121,129,132,156,186,226,229,261,280,297,298). Fully 45% of the infections reported were accompanied by underlying neoplastic disease.…”

Section: Bacillus Sppmentioning

confidence: 99%

Recovery of uncommon bacteria from blood: association with neoplastic disease

Beebe

Koneman

1995

Clin Microbiol Rev

View full text Add to dashboard Cite

Table 6 is a summary of the organisms discussed with a listing of the environmental source, the endogenous source, the predisposing factors including neoplasms, and the postulated mechanisms by which the organism can gain access to the circulation. The evidence considered indicates that the entrance of one of these microorganisms into the bloodstream of a human being depends on the presence of multiplicity of predisposing factors. In the majority of cases of bacteremia due to one of these unusual organisms, two or more predisposing factors are present. Certain predisposing factors, such as cancer chemotherapy or intravenous catheterization, often provide a barrier break, while others, such as liver disease, may render the host immune system less capable of clearing organisms from the circulation. For organisms such as Campy-lobacter, Listeria, and Salmonella spp., attributes that allow the invasion of a healthy host are present and seem to be enhanced by the simultaneous presence of a predisposing condition, such as liver disease, in the host. Although somewhat fragmentary, a number of individual case reports describe bacteremia due to one of these organisms occurring weeks to years after surgery and after other therapeutic measures had effected a supposed cure of a cancer. It may be speculated that cancer patients, even after a cure, are still susceptible to bloodstream invasion by one of the aforementioned organisms by virtue of the presence of one or more predisposing metabolic, physiologic, or immunologic factors, even though these factors may be cryptic. The predominance of hematologic malignancies among cases of bacteremia due to these unusual organisms is also apparent. Although, as pointed out by Keusch (169), the reduction in the performance of immune function in hematologic malignancies compared with solid tumors is likely to be responsible, other associations of certain organisms with specific neoplasms warrant further examination. The frequency of bloodstream infections of Salmonella typhimurium and Capno-cytophaga canimorsus in Hodgkin's disease patients seems likely due to a particular mechanism which infection by these species is favored. The specific nature of these mechanisms remains to be determined. The recovery of any unusual bacterium from blood should warrant a careful consideration of the possibility of underlying disease, especially cancer. Microbiologists should advise clinicians of the unusual nature of the identified organism and provide the counsel that certain neoplastic processes, often accompanied by neutropenia, render the human host susceptible to invasion by almost any bacterium. The recovery of such organisms as C. septicum or S. bovis should prompt the clinician to aggressively seek to identify an occult neoplasm if one has not yet been diagnosed.

show abstract

Section: Bacillus Sppmentioning

confidence: 99%

Recovery of uncommon bacteria from blood: association with neoplastic disease

Beebe

Koneman

1995

Clin Microbiol Rev

View full text Add to dashboard Cite

show abstract

“…For rabbit intestinal necrosis reactions the cell-free filtrates were concentrated four-to seven-fold and ' Turnbull et al (1977a); ' Turnbull (1976); ' Chaslel et al (1977); ' Barnham and Taylor (1977). ***Culture was not available.…”

Section: Toxin Testsmentioning

confidence: 99%

“…Classification of the species under the name B. cereus was fully established in 1952 (Smith et al), and under this name the organism has continued to be recorded as the cause of bacteraemia and septicaemia (Curtis et al, 1967;Crowley, 1970;Leffert et al, 1970;Coonrod et al, 1971;Goullet and PNpin, 1974;Raphael and Donaghue, 1976; Barnham and Taylor, 1977;Chastel et al, 1977), pneumonia and pleurisy (Stopler et al, 1964;LeLourd et al, 1967;Coonrod et al, 1971;Feldman and Pearson, 1974;Leff et al, 1977), endocarditis (Craig et al, 1974;Block et al, 1978), gas gangrenelike infections (Grbschel et al, 1976;Turnbull et al, 1977a), meningitis (Leffert et al, 1970;Raphael and Donaghue, 1976), cerebral necrosis (Turnbull et al, 1977a), middle-ear infection (Lazar and Jurecsak, 1966), osteomyelitis (Solny et al, 1977), and urinary tract infection (Melles et al, 1969).…”

mentioning

confidence: 99%

Severe clinical conditions associated with Bacillus cereus and the apparent involvement of exotoxins.

Turnbull¹,

Jørgensen²,

Kramer³

et al. 1979

J Clin Pathol

107

View full text Add to dashboard Cite

SUMMARY Twenty-one cases of infection with Bacillus cereus are summarised. The histories supplied showed that at least 15 of these were associated with severe or potentially severe symptoms including two deaths. Analysis of the production of exotoxins, including haemolysin and phospholipase, by these strains is given, and the relevance of these metabolites to the severity of the condition is discussed. Three incidents of bovine mastitis resulting from B. cereus and involving three deaths are also included.The observations presented here together with those of previous reports which are reviewed indicate that B. cereus may be of clinical importance, not just as an opportunist but also as an agent of potentially severe infections in its own right.

show abstract

The Sacro-Iliac Joint and Backache

1983

The Lancet

View full text Add to dashboard Cite

A case of Bacillus cereus bacteraemia

Abstract: Summary A case is presented of Bacillus cereus bacteraemia in a patient receiving hepatic perfusion with 5-fluorouracil (5FU) for metastasis from a carcinoma of the breast. The literature concerning systemic B. cereus infections is briefly reviewed.

Cited by 8 publications

References 11 publications

Recovery of uncommon bacteria from blood: association with neoplastic disease

Recovery of uncommon bacteria from blood: association with neoplastic disease

Severe clinical conditions associated with Bacillus cereus and the apparent involvement of exotoxins.

The Sacro-Iliac Joint and Backache

Contact Info

Product

Resources

About