A case of bacteremia caused by Dialister micraerophilus with Enterocloster clostridioformis and Eggerthella lenta in a patient with pyometra

Abstract

Background Infection by Dialister micraerophilus, an obligate anaerobic gram-negative bacillus, has rarely been described, and its clinical characteristics remain unclear. Case presentation We report a case of bacteremia caused by D. micraerophilus, Enterocloster clostridioformis, and Eggerthella lenta in a 47-year-old woman, associated with pyometra. D. micraerophilus was identified using 16S rRNA gene sequencing and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. D. micraerophilus was detected by polymerase chain reaction using D. micraerophilus-specific primers and E. clostridioformis and E. lenta was isolated from the drainage pus sample obtained from the pyometra uterus. The patient achieved a cure after abscess drainage and 2-week antibiotic treatment. Conclusions To the best of our knowledge, this is the first report of D. micraerophilus bacteremia. D. micraerophilus may be associated with gynecological infections. Clinicians should consider both oral and gynecological sites when searching to identify the focus of D. micraerophilus infection.

Bacteremia caused by Enterocloster aldenensis in an oncological patient

“…[ 1 ], siendo posteriormente reclasificado como E. aldenensis por Haas y Blanchard [ 2 ]. Hasta el momento, solo existe un caso documentado de bacteriemia por Enterocloster clostridioformis , junto con Eggerthella lenta y Dialister micraerophilus [ 3 ]. Recientemente hemos observado un caso de bacteriemia debida a E. aldenensis aislado en cultivo puro en un paciente oncológico.…”

“…Las infecciones debidas al género Enterocloster son extremadamente raras. En nuestro conocimiento, esta es la primera bacteriemia descrita en cultivo puro; recientemente se ha publicado una bacteriemia debida a Enterocloster pero de naturaleza polimicrobiana [ 3 ]. Dada su rareza, el conocimiento de su epidemiología y patogenia es escaso.…”