A case of bile duct diverticulum with repeated acute cholangitis due to diverticular stone fall

Azami, Tetsushi; Takano, Yuichi; Kobayashi, Takahiro; Niiya, Fumitaka; Maruoka, Naotaka; Ogawa, Takafumi; Wakabayashi, T.; Matsuo, Keitaro; Tanaka, Kuniya; Nagahama, Masatsugu

doi:10.1007/s12328-021-01462-y

Clin J Gastroenterol

2021

DOI: 10.1007/s12328-021-01462-y

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A case of bile duct diverticulum with repeated acute cholangitis due to diverticular stone fall

Tetsushi Azami

Yuichi Takano

Takahiro Kobayashi

et al.

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2023

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“…Intraductal ultrasound revealed hyperechoic lesions with acoustic shadows in the diverticulum, indicating the presence of stones or fragments accompanied by diverticular stones, and the patient was considered to have recurrent acute cholangitis. 37 A retrospective cohort study illustrated that biliary obstruction may be associated with 30day readmission rates in patients with acute cholangitis. 29 Diabetes mellitus was a risk factor for recurrence of acute cholangitis.…”

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confidence: 99%

Analysis of Pathogenic Bacteria Distribution and Related Factors in Recurrent Acute Cholangitis

Li¹,

Hu²,

Lu³

et al. 2023

IDR

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Background To evaluate the risk factors and prognosis of patients with acute cholangitis recurrence. Methods A total of 503 patients with acute cholangitis admitted to the First Affiliated Hospital of Chongqing Medical University between July 2013 and January 2022 were included in this retrospective observational study, who were followed up for 360 days and divided into relapse group and non-recurrence group according to the recurrence of acute cholangitis. Risk factors and prognosis of patients with acute cholangitis recurrence were analyzed by univariate, multivariate analyses and proportional hazards model. Results A total of 161 patients with recurrent acute cholangitis were identified. Recurrent acute cholangitis usually occurred within 125 days; Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis, and Enterococcus faecium was the most common positive record both in blood and bile culture. In the multivariate analysis, abdominal pain (OR = 2.448, 95% CI = 1.196–5.010, P = 0.014), bile stones (OR = 2.429, 95% CI = 1.024–5.762, P = 0.044), diabetes (OR = 1.790, 95% CI = 1.007–3.182, P = 0.047), pathogen (OR = 3.305, 95% CI = 1.932–5.654, P <0.001), and chronic kidney disease (OR = 2.500, 95% CI = 1.197–5.221, P = 0.015) may be ascertained as the risk factors of acute cholangitis recurrence. The recurrence of acute cholangitis was identified as an independent risk factor for patient death (HR = 4.524, 95% CI = 1.426–14.357, P = 0.010) by Cox proportional-hazards regression. Conclusion Abdominal pain, bile stones, diabetes and chronic kidney disease may be risk factors of acute cholangitis recurrence. Patients with recurrent acute cholangitis have poor prognosis and high mortality. Early control of recurrent risk factors and active intervention are beneficial to high-risk patients.

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mentioning

confidence: 99%

Analysis of Pathogenic Bacteria Distribution and Related Factors in Recurrent Acute Cholangitis

Li¹,

Hu²,

Lu³

et al. 2023

IDR

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A case of bile duct diverticulum with repeated acute cholangitis due to diverticular stone fall

Cited by 1 publication

References 16 publications

Analysis of Pathogenic Bacteria Distribution and Related Factors in Recurrent Acute Cholangitis

Analysis of Pathogenic Bacteria Distribution and Related Factors in Recurrent Acute Cholangitis

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