A Case of Bordetella bronchiseptica Bacteremia in a Patient With COVID-19: Brief Report

Abstract

Bordetella bronchiseptica is a gram-negative coccobacillus that colonizes the respiratory system of mammals such as dogs, cats, rabbits and others and might cause upper respiratory tract infections. Although it can be rarely pathogenic in humans, there are several case reports describing infections in humans. We describe the case of a patient without prolonged immunosuppression or underlying diseases, with bacteremia from Bordetella bronchiseptica, while being treated in a tertiary hospital for COVID-19 infection.

Bordetella bronchiseptica empyema in patient with chronic alcohol use disorder

“…Alcoholism is an ongoing national healthcare crisis with reported 15 million people ages 12 and older meeting criteria for Alcohol Use Disorder according to the 2019 National Survey on Drug Use and Health [ 10 ]. Recently, there have been several reported human cases of B. bronchiseptica infections with risk factors including COVID-19, HIV, lung malignancy and decompensated liver cirrhosis; however, we only found 2 previous case reports of B. bronchiseptica infections with the primary immunocompromising risk factor being related to alcohol use [ 3 , 5 , 9 , 11 , 13 ]. Additionally, a recent case report describes a pig farmer that contracted B. bronchiseptica [ 2 ] .…”

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Bordetella bronchiseptica Co-Infection in a Stem Cell Transplant Patient

“…For example, our patient’s chronic cough began approximately a month before she developed shortness of breath, an important consideration given that chronic cough has been previously associated with human B. bronchiseptica infections [ 11 , 12 ]. Additionally, our case represents at least the second patient diagnosed with B. bronchiseptica pneumonia while receiving nivolumab [ 13 ] and the fourth documented patient co-infected with COVID-19 and B. bronchiseptica [ 14 , 15 , 16 ]. Clinical characteristics of patients co-infected with COVID-19 and B. bronchiseptica are summarized in Table 2 .…”

Safety and Efficacy of the Bordetella bronchiseptica Vaccine Combined with a Vegetable Oil Adjuvant and Multi-Omics Analysis of Its Potential Role in the Protective Response of Rabbits

“…Moreover, Bb could pave the way for other pathogens, in turn leading to several secondary infections, resulting in significant economic losses for farmers [ 5 , 6 ]. Even worse, a case of Bb bacteremia in a patient with COVID-19 was observed [ 7 ], thereby demonstrating the potential of zoonotic transmission between animals and humans.…”