A case of Candida guilliermondii abortion in an Arab mare

Abstract

Ascending infections of equine uterus frequently result in placentitis and abortions; most of these infections are bacterial and are less commonly due to fungi. This report describes an abortion case in an Arab mare due to Candida guilliermondii that was diagnosed via cytological, histological, cultural and biomolecular assays. The histological lesions found were severe necrotizing placentitis associated with fetal pneumonia. To our knowledge this is the first case of C. guilliermondii abortion reported in equine species.

Presence and distribution of yeasts in the reproductive tract in healthy female horses

“…neoformans, G. candidum, R. rubra and Trichosporon cutaneum in sheep and goats [4] and Candida glabrata, Candida famata, C. guilliermondii and T. beigelii in lions [5]. Fungal infections of the vagina, cervix and endometrium can result in stillbirth and neonatal death in cows, buffaloes, dogs and cats [6][7][8][9], and abortion in horses [10][11][12][13][14].…”

Sensibilidade Do Laminocultivo Dermatobac® Para O Diagnóstico Da Endometrite Fúngica Em Éguas

“…Alguns fatores de risco como imunossupressão, manipulação excessiva durante a realização de biotécnicas reprodutivas, abuso no uso de antibióticos, conformação perineal alterada, idade e pluriparidade podem aumentar a incidência das endometrites fúngicas (7) . As espécies de fungos mais comumente isoladas dos quadros de endometrite pertencem ao gênero Candida spp e Aspergillus spp, espécies leveduriformes que podem ser identificadas através de exame microscópico direto realizado a partir de citologia esfoliativa endometrial (8,9) . O diagnóstico da endometrite pode ser realizado por meio de exame ginecológico, palpação retal, ultrassonografia transretal, citologia e cultura de conteúdo uterino (10,11) .…”

Pathology of equine amnionitis and foetal lLoss: clinical and experimental studies

“…are rarely isolated in conjunction with placentitis or abortion, in agreement with the low incidence of this organism in mare reproductive swabs (Hong et al, 1993a;Whitwell, 1988;Albihn et al, 2003;Rickets, 2011;Beltaire et al, 2012). A recent case description of Candida (Meyerozyma) guilliermondii described changes in the placenta similar to other mycotic placental lesions with a thick, brown, gritty covering of the chorionic surface centred mainly around the cervical star region (Stefanetti et al, 2014). Yeast were present in the necrotic superficial debris but absent in the foetal tissues (Stefanetti et al, 2014).…”

“…A recent case description of Candida (Meyerozyma) guilliermondii described changes in the placenta similar to other mycotic placental lesions with a thick, brown, gritty covering of the chorionic surface centred mainly around the cervical star region (Stefanetti et al, 2014). Yeast were present in the necrotic superficial debris but absent in the foetal tissues (Stefanetti et al, 2014). Candida spp.…”

“…Candida spp. in general cause superficial necrosis of the villi with an underlying, primarily mononuclear, inflammatory infiltrate composed of lymphocytes, plasma cells, and macrophages within the chorionic stroma (Hong et al, 1993a;Stefanetti et al, 2014). Foetal lesions range from absent to consisting of a mononuclear alveolar interstitial infiltrate in the lung and periportal regions of the liver (Hong et al, 1993a;Stefanetti et al, 2014).…”