A case of carcinosarcoma of the prostate.

A case of prostatic carcinosarcoma with cytological and immunohistochemical findings

“…Although half of PCSs have developed in patients with a history of prostatic adenocarcinoma [6,8], immunohistocehmical examinations was performed in a few cases [12,13]. In our case, we observed multi-nucleated large sarcomatous cells …”

“…Macroscopically, the resected prostate tumor was measuring 8x4.5x4 cm (Figure 5), and the surgical margins were free from the tumor. Cytology of the cut-surface of the tumor at the PE revealed the presence of two types of tumor cells with different origin: one was an adenocarcinoma like cells with a sheet formation (Figure 6A), and the other was big sarcomatous cells with a marked nuclear We performed cytological diagnosis of the present case, as the cytological findings were useful for the diagnosis of the PCS [12,13]. In PCSs reported, adenocarcinoma was usually high grade [6].…”

“…Some PCSs may also be referred to as sarcomatoid carcinoma [6][7][8][9]11]. Also, only a few studies on the cytological and immunohistochemical findings of this rare malignancy were described [12,13].…”