A Case of Cardiac Undifferentiated Pleomorphic Sarcoma With Right Ventricular Outflow Tract Obstruction

Abstract

Malignant tumors originating from the heart are extremely rare. Here, we report a case of severe right ventricular outflow tract (RVOT) stenosis in a 67 year-old woman caused by a massive intimal sarcoma that required venous-arterial extracorporeal membrane oxygenation to support systemic circulation. Surgical resection and RVOT reconstruction with tricuspid and pulmonary valve replacement were performed. The pathological diagnosis was cardiac undifferentiated pleomorphic sarcoma. Although the patient was discharged 65 days after surgery in good condition, she subsequently died from multiple metastases detected in the early phase after surgery.

Undifferentiated pleomorphic prostate sarcoma: a rare clinical case and systematic literature review

“…К наиболее частым ее локализациям относят мягкие ткани конечностей, живота, малого таза и грудной клетки [6]. В некоторых случаях недифференцированная плеоморфная саркома может поражать печень [7], легкие и плевру [8], сердце [9], тонкий кишечник [10]. Наиболее редким органом-мишенью является предста-тельная железа, общее количество насчитываемых на сегодняшний день случаев ее поражения не превышает 50.…”