A Case of Chilblains-like Lesions Post SARS-CoV-2 Vaccine?

Silkoski, Molly; Quin, Kai; Jarjour, Wael

doi:10.3899/jrheum.210226

Cited by 10 publications

(16 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, a causal association between immunization against COVID-19 and the development of chilblainlike lesions cannot be demonstrated: to date, only a few isolated reports have been published (5)(6)(7)(8). A study on an international registry of 803 vaccine reactions reported 3 cases of chilblain-like lesions (9).…”

Section: Discussionmentioning

confidence: 99%

Chilblain-like Lesions after COVID-19 Vaccination: A Case Series

Russo¹,

Cozzani

Micalizzi³

et al. 2022

Acta Derm Venereol

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Chilblain-like Lesions after COVID-19 Vaccination: A Case Series

Russo¹,

Cozzani

Micalizzi³

et al. 2022

Acta Derm Venereol

View full text Add to dashboard Cite

show abstract

“…Histologic examination revealed findings indistinguishable from idiopathic and COVID‐19‐related perniones. 40,42 …”

Section: Nail Changes Induced By Sars‐cov‐2 Infectionmentioning

confidence: 99%

“…Recently, some cases of pernio‐like lesions were reported that developed on the hands and/ or feet a few days after vaccination against COVID‐19 with RNA‐based vaccines (BionTec/ Pfizer, Moderna) 39–42 . Histologic examination revealed findings indistinguishable from idiopathic and COVID‐19‐related perniones.…”

Section: Nail Changes Induced By Sars‐cov‐2 Infectionmentioning

confidence: 99%

Nails and COVID ‐19 – A comprehensive review of clinical findings and treatment

Wollina

Kanitakis

Baran

2021

Dermatologic Therapy

View full text Add to dashboard Cite

The SARS‐CoV‐2 infection, responsible for COVID‐19, has raised the interest for infection‐associated muco‐cutaneous symptoms. While dermatologic symptoms in general gained an increasing awareness, affection of the nail organ has been mentioned only recently. We provide a narrative review on COVID‐19 manifestation on the nail organ and add symptoms induced by personal protective measures and SARS‐CoV‐2 vaccination. Available treatment options are discussed.

show abstract

“…Contrastingly, Polysorbate 80 is a vaccine excipient in the Johnson & Johnson COVID-19 vaccine [ 35 ]. Cutaneous adverse events to these vaccine excipients have been reported, including allergic reactions at the injection site (COVID arm), chilblain-like lesion, urticaria, and anaphylaxis [ 36 , 37 , 38 ].…”

Section: Introductionmentioning

confidence: 99%

The Impact of COVID-19 Pandemic on Dermatological Conditions: A Novel, Comprehensive Review

et al. 2022

View full text Add to dashboard Cite

Background: The earliest cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2019. Since the declaration as a pandemic on 11 March 2020, further dermatological conditions continue to be documented. We herein present a novel literature review of dermatological manifestations associated with the Coronavirus Disease 2019 (COVID-19) pandemic. To date, this literature review is the first broad-spectrum examination that analyzes a range of dermatological manifestations related to the COVID-19 pandemic: infection, vaccinations, personal protective equipment (PPE), and psychosocial factors. Methods: A detailed literature search was conducted using key terms for cutaneous manifestations associated with the scope of this review. The search retrieved 2199 articles. Results: The COVID-19 pandemic has triggered a significant range of dermatologic sequela. Etiologies of lesions continue to be investigated. Proposed mechanisms include inflammatory response to spike protein, vitamin D deficiency, ACE2 receptor activation, androgen levels, and increased psychological stress. One prominent mechanism describes viral spike protein invasion into the dermis by binding to the angiotensin-converting enzyme 2 (ACE-2) receptors in keratinocytes, with a secondary immunological response. Conclusions: Dermatologists play an integral role in the proper diagnosis and treatment of COVID-related lesions. Early treatment regimens and timely prophylaxis have been shown to safely reduce infection-related dermatological sequelae. Additional investigations and data collection can reduce disease burden and improve overall prognosis.

show abstract

A Case of Chilblains-like Lesions Post SARS-CoV-2 Vaccine?

Cited by 10 publications

References 5 publications

Chilblain-like Lesions after COVID-19 Vaccination: A Case Series

Chilblain-like Lesions after COVID-19 Vaccination: A Case Series

Nails and COVID ‐19 – A comprehensive review of clinical findings and treatment

The Impact of COVID-19 Pandemic on Dermatological Conditions: A Novel, Comprehensive Review

Contact Info

Product

Resources

About