A 37-year-old man developed coronavirus disease 2019 following treatment doxorubicin for Kaposi sarcoma. The man, who had HIV, presented to receive the second dose of doxorubicin chemotherapy [dosage and route not stated] for his Kaposi sarcoma. At that time, he reported having high-grade fever associated with a sore throat, mild cough, occasional headaches, chills and night sweats for the past 2 days. He was thus admitted for further evaluation. On systematic examination, he did not show shortness of breath, chest pain, diarrhoea, skin changes or loss of smell or taste. He was diagnosed with AIDS 2 years prior, and was non-adherent to the antiretroviral therapy. Recently he had recovered from severe pneumocystis pneumonia. He was diagnosed with Kaposi sarcoma 2 month ago, for which he had been receiving doxorubicin. He was adherent with his antiretroviral therapy from the diagnosis of Kaposi's sarcoma. His other medical history was significant for treated chronic hepatitis-C, syphilis, anxiety and depression. He had been receiving bictegravir/emtricitabine/tenofovir-alafenamide along with various other concomitant medications. He was allergic to cotrimoxazole and was known intolerant to dapsone. He never smoked and also denied consumption of alcohol. However, he had a history of methamphetamine and marijuana use, which he had left for 3 years. His family history was non-significant. He did not travel outside Nebraska state recently nor had any exposure to COVID-19 or sick patients. On evaluation, his temperature was 38.2°C, heart rate of 118 beats/minute and BP was 136/72mm Hg, respiratory rate of 20 breaths/minute, and his oxygen saturation was 99% on room air. He had normal respiratory effort, and the lungs were clear to auscultation. On examination, a healed incision in the right groin, pruritic rash in bilateral inguinal areas, shallow perianal ulcers with minimal bleeding were observed [aetiology not stated]. Laboratory investigations showed leucocytosis and mildly elevated procalcitonin. Also, an increased HIV viral load was noted. A chest x-ray demonstrated no signs of cardio/pulmonary disease. An abdominal and pelvis CT scan revealed no focus of infection. Subsequently, sample was taken to perform COVID-19 qualitative test.The man was empirically treated with vancomycin, cefepime, metronidazole, fluconazole and miconazole, considering his recent methicillin-resistant Staphylococcus aureus (MRSA) abscess and a current cutaneous candidiasis infection [aetiologies of these infections not stated]. On day 3 of admission, the COVID-19 test resulted positive [duration of treatment to reaction onset not stated]. Consequently, his antibiotics were discontinued. Throughout the hospital stay, he did not require any supplemental oxygen therapy. Eventually, all the COVID-19 symptoms resolved completely. Anticoagulation therapy was not given due to his thrombocytopenia, and a recent episode of rectal bleeding. Thereafter, on day 4 of hospitalisation, he was discharged in stable condition. He was then recommended to s...