A case of delusional disorder, somatic type with remarkable improvement of clinical symptoms and single photon emission computed tomograpy findings following modified electroconvulsive therapy

Ota, Miho; Mizukami, Katsuyoshi; Katano, Tsunahiro; Sato, Sadao; Takeda, Takeshi; Asada, Takashi

doi:10.1016/s0278-5846(03)00118-0

Cited by 26 publications

(29 citation statements)

References 8 publications

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“…In the literature, some neuroimaging case reports on oral cenesthopathy or delusional disorder, somatic type, in the oral area have shown the attenuation of right-side-predominant rCBF asymmetry in parallel with the improvement of symptoms by paroxetine, 8 mECT, 11 and the combination of mECT and perospirone. 10 In the present cases, we found similar rCBF change to former case reports regardless of treatment method.…”

Section: Discussionmentioning

confidence: 99%

“…7 In some case reports, although typical antipsychotics hardly improved the symptoms of oral cenesthopathy, 2 the right-side-predominant rCBF disappeared after successful treatment using paroxetine, 8 risperidone, 9 or modified electroconvulsive therapy (mECT). 10,11 However, the studies scrutinizing the rCBF change before and after successful treatment are still a few so far. We present 2 cases of oral cenesthopathy, who responded well to aripiprazole, a dopamine partial agonist, and whose asymmetric rCBF patterns were attenuated after successful treatment.…”

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confidence: 99%

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Two Cases of Oral Somatic Delusions Ameliorated With Brain Perfusion Asymmetry: A Case Report

Umezaki¹,

Uezato²,

Toriihara³

et al. 2017

Clin Neuropharm

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BackgroundOral cenesthopathy is the complaint of abnormal oral sensation where no underlying organic cause can be identified. It is also called oral dysesthesia or oral somatic delusion and classified as delusional disorder, somatic type. The patients with oral cenesthopathy show right > left asymmetric regional cerebral blood flow (rCBF) in the broad brain region. However, the studies scrutinizing the rCBF change before and after the successful treatment are still a few so far.CaseWe present 2 cases of oral cenesthopathy, who responded well to aripiprazole. The asymmetric rCBF patterns were attenuated after successful treatment in both cases.ConclusionsWe found a marked improvement of oral cenesthopathy with aripiprazole. It is suggested that right > left rCBF asymmetry in the frontal and temporal lobes and thalamus, and the dopaminergic and serotonergic dysfunctions are involved in the pathology of oral cenesthopathy.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Two Cases of Oral Somatic Delusions Ameliorated With Brain Perfusion Asymmetry: A Case Report

Umezaki¹,

Uezato²,

Toriihara³

et al. 2017

Clin Neuropharm

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“…Subsequent large population studies have shown a prevalence of 0.18% in a Finnish sample aged over 30 (Suvisaari 2009), which equates with a finding of 2% in 378 982 out-patients and in-patients at a hospital in Thailand between 2003(Kosiyakul 2008. In the UK, of 227 patients presenting to an early intervention service over a 3-year period, 7% were found to have delusional disorder (Proctor 2004).…”

Section: Constitutional Vulnerabilitiesmentioning

confidence: 80%

“…A case report of somatic delusional disorder responding to ECT did not sufficiently exclude an affective component (Ota 2003). Furthermore, given that the response of psychotic phenomena in schizophrenia to ECT is not long lasting, there would appear to be no indication for the use of ECT in delusional disorder (for a review, see Fear 2005).…”

Section: Electroconvulsive Therapymentioning

confidence: 99%

Recent developments in the management of delusional disorders

Fear¹

2013

Adv. psychiatr. treat

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SummaryDelusional disorder, rare in clinical practice, remains one of the most enigmatic conditions in psychiatry. Linked to schizophrenia spectrum disorders since the mid-20th century, recent work has confirmed 19th-century notions of an aetiology based on attentional biases and personality dimensions. Unfortunately, the literature exists largely as case reports and series, often published as ‘curiosities’, and therefore lacks the rigour of formal diagnosis. This article reviews current thinking on aetiology and epidemiology, considers diagnosis, and reviews recent work on physical and psychological therapies. It concludes that delusional disorder is likely to respond well to treatment with standard antipsychotics, often at low doses, but that adherence and concordance remain particular problems. Cognitive therapy has been shown to be beneficial but is time-consuming and resource-intensive. Selective serotonin reuptake inhibitors may profit further investigation. There remains considerable scope for investigation of this fascinating condition.

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“…Two showed resolution of their delusions while one showed little response. More recently, Ota et al (2003) wrote about remarkable improvement in symptoms of delusional disorder, somatic type, in one individual treated with modified electroconvulsive therapy.…”

Section: Treatment Options For Patients With Delusional Disordermentioning

confidence: 99%

Pharmacotherapy of delusional disorders in the context of offending and the potential for compulsory treatment

Smith¹,

Buckley

2006

Behavioral Sci & The Law

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Delusional disorder is an uncommon mental illness with an estimated prevalence of 0.03%. Its low prevalence has likely contributed to the paucity of research interest in this area, leading to substantial gaps in knowledge concerning its treatment and management. In the absence of a robust literature, most clinicians rely on their experience and guidelines for treating schizophrenia when treating patients with delusional disorder. This article reviews the available literature that is specific to the treatment of delusional disorder. In addition, it focuses on specific forensic and medicolegal aspects of managing patients with delusional disorder.

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A case of delusional disorder, somatic type with remarkable improvement of clinical symptoms and single photon emission computed tomograpy findings following modified electroconvulsive therapy

Cited by 26 publications

References 8 publications

Two Cases of Oral Somatic Delusions Ameliorated With Brain Perfusion Asymmetry: A Case Report

Two Cases of Oral Somatic Delusions Ameliorated With Brain Perfusion Asymmetry: A Case Report

Recent developments in the management of delusional disorders

Pharmacotherapy of delusional disorders in the context of offending and the potential for compulsory treatment

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